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    Phaf1 phagosome assembly factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 234678, updated on 8-Jul-2021

    Summary

    Official Symbol
    Phaf1provided by MGI
    Official Full Name
    phagosome assembly factor 1provided by MGI
    Primary source
    MGI:MGI:2443049
    See related
    Ensembl:ENSMUSG00000031889
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Li; Lin10; BC006874; D230025D16Rik
    Expression
    Ubiquitous expression in lung adult (RPKM 24.9), liver adult (RPKM 16.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Phaf1 in Genome Data Viewer
    Location:
    8; 8 D3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (105951779..105979685)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (105225146..105253053)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (107749088..107776953)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 22063 Neighboring gene core binding factor beta Neighboring gene expressed sequence AI225912 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 Neighboring gene TNFRSF1A-associated via death domain Neighboring gene F-box and leucine-rich repeat protein 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Clone Names

    • MGC6480

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables PDZ domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables glutamate receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in Golgi to plasma membrane protein transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in phagophore assembly site ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    phagosome assembly factor 1; UPF0183 protein C16orf70 homolog
    Names
    lin-10 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001379098.1NP_001366027.1  phagosome assembly factor 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC124713
      Conserved Domains (1) summary
      pfam03676
      Location:15437
      UPF0183; Uncharacterized protein family (UPF0183)
    2. NM_145604.3NP_663579.2  phagosome assembly factor 1 isoform 2

      See identical proteins and their annotated locations for NP_663579.2

      Status: VALIDATED

      Source sequence(s)
      AC124713
      Consensus CDS
      CCDS22593.1
      UniProtKB/Swiss-Prot
      Q922R1
      Related
      ENSMUSP00000034361.4, ENSMUST00000034361.10
      Conserved Domains (1) summary
      pfam03676
      Location:15407
      UPF0183; Uncharacterized protein family (UPF0183)

    RNA

    1. NR_166491.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124713
    2. NR_166492.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124713
      Related
      ENSMUST00000141957.8
    3. NR_166493.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC124713
      Related
      ENSMUST00000124113.8

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      105951779..105979685
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530888.4XP_006530951.1  UPF0183 protein C16orf70 homolog isoform X2

      Conserved Domains (1) summary
      pfam03676
      Location:2256
      UPF0183; Uncharacterized protein family (UPF0183)
    2. XM_036153966.1XP_036009859.1  UPF0183 protein C16orf70 homolog isoform X1

      Conserved Domains (1) summary
      pfam03676
      Location:1267
      UPF0183; Uncharacterized protein family (UPF0183)
    3. XM_036153968.1XP_036009861.1  UPF0183 protein C16orf70 homolog isoform X4

      Conserved Domains (1) summary
      pfam03676
      Location:2226
      UPF0183; Uncharacterized protein family (UPF0183)
    4. XM_036153967.1XP_036009860.1  UPF0183 protein C16orf70 homolog isoform X3

      Conserved Domains (1) summary
      pfam03676
      Location:1237
      UPF0183; Uncharacterized protein family (UPF0183)
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