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    Ddx49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [ Mus musculus (house mouse) ]

    Gene ID: 234374, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ddx49provided by MGI
    Official Full Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 49provided by MGI
    Primary source
    MGI:MGI:2136689
    See related
    Ensembl:ENSMUSG00000057788
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    R27090_2
    Expression
    Ubiquitous expression in ovary adult (RPKM 41.1), cerebellum adult (RPKM 36.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ddx49 in Genome Data Viewer
    Location:
    8; 8 B3.3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (70292866..70302511, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (72816765..72826351, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene armadillo repeat containing 6 Neighboring gene SURP and G patch domain containing 2 Neighboring gene predicted gene, 38427 Neighboring gene homer scaffolding protein 3 Neighboring gene coatomer protein complex, subunit epsilon Neighboring gene ceramide synthase 1 Neighboring gene growth differentiation factor 1 Neighboring gene UPF1 regulator of nonsense transcripts homolog (yeast)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    probable ATP-dependent RNA helicase DDX49
    Names
    DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 27
    DEAD box protein 49
    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 49
    NP_001020093.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024922.2NP_001020093.2  probable ATP-dependent RNA helicase DDX49

      See identical proteins and their annotated locations for NP_001020093.2

      Status: VALIDATED

      Source sequence(s)
      AA544796, BC085301
      Consensus CDS
      CCDS22364.1
      UniProtKB/Swiss-Prot
      Q4FZF3
      Related
      ENSMUSP00000008004.9, ENSMUST00000008004.9
      Conserved Domains (4) summary
      PRK11192
      Location:4459
      PRK11192; ATP-dependent RNA helicase SrmB; Provisional
      cd00079
      Location:218351
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      cd00268
      Location:4206
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
      cl19511
      Location:363454
      DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)

    RNA

    1. NR_157058.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AA544796, BB578972, BC085301

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      70292866..70302511 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_379040.3 RNA Sequence

      Related
      ENSMUST00000144890.7
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