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    Pcid2 PCI domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 234069, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pcid2provided by MGI
    Official Full Name
    PCI domain containing 2provided by MGI
    Primary source
    MGI:MGI:2443003
    See related
    Ensembl:ENSMUSG00000038542
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A730042J05Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 8.8), thymus adult (RPKM 6.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Pcid2 in Genome Data Viewer
    Location:
    8; 8 A1.1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (13125476..13155343, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (13075476..13105343, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (13077525..13105343, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene coagulation factor VII Neighboring gene coagulation factor X Neighboring gene protein Z, vitamin K-dependent plasma glycoprotein Neighboring gene cullin 4A Neighboring gene microRNA 7065 Neighboring gene lysosomal-associated membrane protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cysteine-type endopeptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nuclear retention of pre-mRNA at the site of transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in poly(A)+ mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of B cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of mitotic cell cycle spindle assembly checkpoint IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of mitotic cell cycle spindle assembly checkpoint ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of mRNA stability ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spleen development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in transcription elongation from RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear pore nuclear basket ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of transcription export complex 2 IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of transcription export complex 2 ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    PCI domain-containing protein 2
    Names
    CSN12-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178708.3NP_848823.2  PCI domain-containing protein 2

      See identical proteins and their annotated locations for NP_848823.2

      Status: VALIDATED

      Source sequence(s)
      AK042945, AK163697, BC118533, BY281425
      Consensus CDS
      CCDS52484.1
      UniProtKB/Swiss-Prot
      Q8BFV2
      Related
      ENSMUSP00000133204.2, ENSMUST00000164416.8
      Conserved Domains (1) summary
      cl02111
      Location:80393
      PCI; PCI domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      13125476..13155343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508761.4XP_006508824.1  PCI domain-containing protein 2 isoform X1

      Conserved Domains (1) summary
      cl02111
      Location:2226
      PCI; PCI domain
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