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    Atxn2l ataxin 2-like [ Mus musculus (house mouse) ]

    Gene ID: 233871, updated on 23-Jun-2021

    Summary

    Official Symbol
    Atxn2lprovided by MGI
    Official Full Name
    ataxin 2-likeprovided by MGI
    Primary source
    MGI:MGI:2446242
    See related
    Ensembl:ENSMUSG00000032637
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A; A2; A2D; A2LG; A2RP; A2lp; Atxnl2
    Expression
    Ubiquitous expression in testis adult (RPKM 219.2), thymus adult (RPKM 135.9) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Atxn2l in Genome Data Viewer
    Location:
    7; 7 F3
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126090880..126106991, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (126491708..126507819, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (133635222..133646816, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46001 Neighboring gene Tu translation elongation factor, mitochondrial Neighboring gene RIKEN cDNA 4930456A14 gene Neighboring gene eukaryotic translation initiation factor 3, subunit C Neighboring gene predicted gene, 24596 Neighboring gene predicted gene, 25579

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in stress granule assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in stress granule assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasmic stress granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasmic stress granule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ataxin-2-like protein
    Names
    ataxin 2 related protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347658.1NP_001334587.1  ataxin-2-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC125322
      Consensus CDS
      CCDS85413.1
      UniProtKB/TrEMBL
      Q3TGG2
      Related
      ENSMUSP00000132959.2, ENSMUST00000167759.8
    2. NM_001361487.1NP_001348416.1  ataxin-2-like protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC125322
      Conserved Domains (4) summary
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:121194
      SM-ATX; Ataxin 2 SM domain
      cl25764
      Location:749950
      PAT1; Topoisomerase II-associated protein PAT1
      cl26464
      Location:334940
      Atrophin-1; Atrophin-1 family
    3. NM_183020.2NP_898841.1  ataxin-2-like protein isoform 1

      See identical proteins and their annotated locations for NP_898841.1

      Status: VALIDATED

      Source sequence(s)
      AC125322, BC054483
      Consensus CDS
      CCDS21831.1
      UniProtKB/Swiss-Prot
      Q7TQH0
      Related
      ENSMUSP00000035415.9, ENSMUST00000040202.15
      Conserved Domains (2) summary
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:120188
      SM-ATX; Ataxin 2 SM domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      126090880..126106991 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507725.3XP_006507788.1  ataxin-2-like protein isoform X5

      UniProtKB/Swiss-Prot
      Q7TQH0
      Conserved Domains (4) summary
      PHA03247
      Location:334940
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam09770
      Location:8301035
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:118194
      SM-ATX; Ataxin 2 SM domain
    2. XM_030242516.2XP_030098376.1  ataxin-2-like protein isoform X4

      Conserved Domains (5) summary
      PHA03247
      Location:5471073
      PHA03247; large tegument protein UL36; Provisional
      COG5180
      Location:207532
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam09770
      Location:749950
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:118194
      SM-ATX; Ataxin 2 SM domain
    3. XM_006507721.3XP_006507784.1  ataxin-2-like protein isoform X2

      UniProtKB/TrEMBL
      A0A0U1RPL0
      Related
      ENSMUSP00000146023.2, ENSMUST00000206577.2
      Conserved Domains (5) summary
      PHA03247
      Location:5881031
      PHA03247; large tegument protein UL36; Provisional
      COG5180
      Location:207532
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam09770
      Location:749950
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:118194
      SM-ATX; Ataxin 2 SM domain
    4. XM_006507723.3XP_006507786.1  ataxin-2-like protein isoform X3

      See identical proteins and their annotated locations for XP_006507786.1

      Conserved Domains (4) summary
      PHA03247
      Location:401946
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam09770
      Location:755956
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:118194
      SM-ATX; Ataxin 2 SM domain
    5. XM_006507722.3XP_006507785.1  ataxin-2-like protein isoform X3

      See identical proteins and their annotated locations for XP_006507785.1

      Conserved Domains (4) summary
      PHA03247
      Location:401946
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam09770
      Location:755956
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:118194
      SM-ATX; Ataxin 2 SM domain
    6. XM_006507720.4XP_006507783.1  ataxin-2-like protein isoform X1

      See identical proteins and their annotated locations for XP_006507783.1

      Conserved Domains (4) summary
      PHA03247
      Location:401946
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam09770
      Location:755956
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:118194
      SM-ATX; Ataxin 2 SM domain
    7. XM_011241775.2XP_011240077.1  ataxin-2-like protein isoform X1

      See identical proteins and their annotated locations for XP_011240077.1

      Conserved Domains (4) summary
      PHA03247
      Location:401946
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam09770
      Location:755956
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:118194
      SM-ATX; Ataxin 2 SM domain
    8. XM_006507728.3XP_006507791.1  ataxin-2-like protein isoform X17

      Conserved Domains (2) summary
      PHA03247
      Location:3499
      PHA03247; large tegument protein UL36; Provisional
      PRK14971
      Location:427502
      PRK14971; DNA polymerase III subunit gamma/tau
    9. XM_030242522.2XP_030098382.1  ataxin-2-like protein isoform X11

      Conserved Domains (4) summary
      PHA03247
      Location:248854
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:176238
      LsmAD; LsmAD domain
      pfam09770
      Location:663864
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:32108
      SM-ATX; Ataxin 2 SM domain
    10. XM_030242521.2XP_030098381.1  ataxin-2-like protein isoform X11

      Conserved Domains (4) summary
      PHA03247
      Location:248854
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:176238
      LsmAD; LsmAD domain
      pfam09770
      Location:663864
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:32108
      SM-ATX; Ataxin 2 SM domain
    11. XM_030242519.2XP_030098379.1  ataxin-2-like protein isoform X9

      Conserved Domains (5) summary
      PHA03247
      Location:248854
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:7821006
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      pfam06741
      Location:176238
      LsmAD; LsmAD domain
      pfam09770
      Location:663864
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:32108
      SM-ATX; Ataxin 2 SM domain
    12. XM_030242520.2XP_030098380.1  ataxin-2-like protein isoform X10

      Conserved Domains (3) summary
      PHA03247
      Location:315860
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:176238
      LsmAD; LsmAD domain
      pfam14438
      Location:35108
      SM-ATX; Ataxin 2 SM domain
    13. XM_036153014.1XP_036008907.1  ataxin-2-like protein isoform X10

      Conserved Domains (3) summary
      PHA03247
      Location:315860
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:176238
      LsmAD; LsmAD domain
      pfam14438
      Location:35108
      SM-ATX; Ataxin 2 SM domain
    14. XM_030242518.2XP_030098378.1  ataxin-2-like protein isoform X8

      Conserved Domains (4) summary
      PHA03247
      Location:315860
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:176238
      LsmAD; LsmAD domain
      pfam09770
      Location:669870
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:32108
      SM-ATX; Ataxin 2 SM domain
    15. XM_030242527.1XP_030098387.1  ataxin-2-like protein isoform X17

      Conserved Domains (2) summary
      PHA03247
      Location:3499
      PHA03247; large tegument protein UL36; Provisional
      PRK14971
      Location:427502
      PRK14971; DNA polymerase III subunit gamma/tau
    16. XM_017322209.2XP_017177698.1  ataxin-2-like protein isoform X13

      Conserved Domains (4) summary
      PHA03247
      Location:281826
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:142204
      LsmAD; LsmAD domain
      pfam09770
      Location:635836
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:174
      SM-ATX; Ataxin 2 SM domain
    17. XM_030242526.2XP_030098386.1  ataxin-2-like protein isoform X16

      Related
      ENSMUSP00000125881.3, ENSMUST00000166682.9
      Conserved Domains (4) summary
      PHA03247
      Location:214820
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:142204
      LsmAD; LsmAD domain
      pfam09770
      Location:710915
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:174
      SM-ATX; Ataxin 2 SM domain
    18. XM_030242524.1XP_030098384.1  ataxin-2-like protein isoform X14

      Conserved Domains (4) summary
      PHA03247
      Location:214820
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:142204
      LsmAD; LsmAD domain
      pfam09770
      Location:629830
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:174
      SM-ATX; Ataxin 2 SM domain
    19. XM_030242523.2XP_030098383.1  ataxin-2-like protein isoform X12

      Conserved Domains (4) summary
      PHA03247
      Location:248854
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:176238
      LsmAD; LsmAD domain
      pfam09770
      Location:663864
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:32108
      SM-ATX; Ataxin 2 SM domain
    20. XM_030242517.1XP_030098377.1  ataxin-2-like protein isoform X7

      Conserved Domains (4) summary
      PHA03247
      Location:277883
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:205267
      LsmAD; LsmAD domain
      pfam09770
      Location:692893
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:61137
      SM-ATX; Ataxin 2 SM domain
    21. XM_030242525.2XP_030098385.1  ataxin-2-like protein isoform X15

      Conserved Domains (4) summary
      PHA03247
      Location:315860
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:176238
      LsmAD; LsmAD domain
      pfam09770
      Location:790957
      PAT1; Topoisomerase II-associated protein PAT1
      pfam14438
      Location:32108
      SM-ATX; Ataxin 2 SM domain
    22. XM_036153013.1XP_036008906.1  ataxin-2-like protein isoform X6

      Conserved Domains (3) summary
      PHA03247
      Location:344889
      PHA03247; large tegument protein UL36; Provisional
      pfam06741
      Location:205267
      LsmAD; LsmAD domain
      pfam14438
      Location:64137
      SM-ATX; Ataxin 2 SM domain
    23. XM_036153015.1XP_036008908.1  ataxin-2-like protein isoform X17

      Conserved Domains (2) summary
      PHA03247
      Location:3499
      PHA03247; large tegument protein UL36; Provisional
      PRK14971
      Location:427502
      PRK14971; DNA polymerase III subunit gamma/tau
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