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    Atxn2l ataxin 2-like [ Mus musculus (house mouse) ]

    Gene ID: 233871, updated on 31-Jan-2019

    Summary

    Official Symbol
    Atxn2lprovided by MGI
    Official Full Name
    ataxin 2-likeprovided by MGI
    Primary source
    MGI:MGI:2446242
    See related
    Ensembl:ENSMUSG00000032637
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A2D; A2LG; A2RP; A2lp; Atxnl2
    Expression
    Ubiquitous expression in testis adult (RPKM 219.2), thymus adult (RPKM 135.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Atxn2l in Genome Data Viewer
    Location:
    7; 7 F3
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (126491708..126503644, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (133635222..133646816, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 46001 Neighboring gene Tu translation elongation factor, mitochondrial Neighboring gene RIKEN cDNA 4930456A14 gene Neighboring gene eukaryotic translation initiation factor 3, subunit C Neighboring gene ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) Neighboring gene microRNA 7059

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    regulation of cytoplasmic mRNA processing body assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cytoplasmic mRNA processing body assembly ISO
    Inferred from Sequence Orthology
    more info
     
    stress granule assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    stress granule assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic stress granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasmic stress granule ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ataxin-2-like protein
    Names
    ataxin 2 related protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347658.1NP_001334587.1  ataxin-2-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC125322
      Consensus CDS
      CCDS85413.1
      UniProtKB/TrEMBL
      Q3TGG2
    2. NM_001361487.1NP_001348416.1  ataxin-2-like protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC125322
      Conserved Domains (4) summary
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:121194
      SM-ATX; Ataxin 2 SM domain
      cl25764
      Location:749950
      PAT1; Topoisomerase II-associated protein PAT1
      cl26464
      Location:334940
      Atrophin-1; Atrophin-1 family
    3. NM_183020.2NP_898841.1  ataxin-2-like protein isoform 1

      See identical proteins and their annotated locations for NP_898841.1

      Status: VALIDATED

      Source sequence(s)
      AC125322, BC054483
      Consensus CDS
      CCDS21831.1
      UniProtKB/Swiss-Prot
      Q7TQH0
      Related
      ENSMUSP00000035415.8, ENSMUST00000040202.14
      Conserved Domains (2) summary
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:120188
      SM-ATX; Ataxin 2 SM domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      126491708..126503644 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507725.2XP_006507788.1  ataxin-2-like protein isoform X4

      UniProtKB/Swiss-Prot
      Q7TQH0
      Conserved Domains (2) summary
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:120188
      SM-ATX; Ataxin 2 SM domain
    2. XM_006507721.2XP_006507784.1  ataxin-2-like protein isoform X2

      UniProtKB/TrEMBL
      A0A0U1RPL0
      Related
      ENSMUSP00000146023.1, ENSMUST00000206577.1
      Conserved Domains (3) summary
      pfam03153
      Location:758939
      TFIIA; Transcription factor IIA, alpha/beta subunit
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:120188
      SM-ATX; Ataxin 2 SM domain
    3. XM_006507723.2XP_006507786.1  ataxin-2-like protein isoform X3

      See identical proteins and their annotated locations for XP_006507786.1

      Conserved Domains (2) summary
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:120188
      SM-ATX; Ataxin 2 SM domain
    4. XM_006507722.2XP_006507785.1  ataxin-2-like protein isoform X3

      See identical proteins and their annotated locations for XP_006507785.1

      Conserved Domains (2) summary
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:120188
      SM-ATX; Ataxin 2 SM domain
    5. XM_006507720.2XP_006507783.1  ataxin-2-like protein isoform X1

      See identical proteins and their annotated locations for XP_006507783.1

      Conserved Domains (3) summary
      pfam03153
      Location:8801072
      TFIIA; Transcription factor IIA, alpha/beta subunit
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:120188
      SM-ATX; Ataxin 2 SM domain
    6. XM_011241775.1XP_011240077.1  ataxin-2-like protein isoform X1

      See identical proteins and their annotated locations for XP_011240077.1

      Conserved Domains (3) summary
      pfam03153
      Location:8801072
      TFIIA; Transcription factor IIA, alpha/beta subunit
      pfam06741
      Location:262324
      LsmAD; LsmAD domain
      pfam14438
      Location:120188
      SM-ATX; Ataxin 2 SM domain
    7. XM_017322209.1XP_017177698.1  ataxin-2-like protein isoform X6

      Related
      ENSMUSP00000125881.2, ENSMUST00000166682.8
    8. XM_006507728.1XP_006507791.1  ataxin-2-like protein isoform X7

      Conserved Domains (1) summary
      pfam03153
      Location:317498
      TFIIA; Transcription factor IIA, alpha/beta subunit
    9. XM_006507726.2XP_006507789.1  ataxin-2-like protein isoform X5

      Related
      ENSMUSP00000132959.1, ENSMUST00000167759.7
      Conserved Domains (2) summary
      pfam06741
      Location:176238
      LsmAD; LsmAD domain
      pfam14438
      Location:34102
      SM-ATX; Ataxin 2 SM domain
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