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    Ipo7 importin 7 [ Mus musculus (house mouse) ]

    Gene ID: 233726, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ipo7provided by MGI
    Official Full Name
    importin 7provided by MGI
    Primary source
    MGI:MGI:2152414
    See related
    Ensembl:ENSMUSG00000066232
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Im; Ra; Imp7; Ranbp7; C330016G14; A330055O14Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 27.1), placenta adult (RPKM 21.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ipo7 in Genome Data Viewer
    Location:
    7; 7 E3
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (109617522..109655816)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (110018315..110056609)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (117161939..117198628)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 41B Neighboring gene RIKEN cDNA 1600010M07 gene Neighboring gene predicted gene, 23100 Neighboring gene predicted gene, 25636 Neighboring gene small nucleolar RNA, H/ACA box 23 Neighboring gene zinc finger protein 143 Neighboring gene WEE 1 homolog 1 (S. pombe)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SMAD binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables histone binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein import into nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    importin-7
    Names
    RAN binding protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362172.2NP_001349101.1  importin-7 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC121995, AC140235
      Conserved Domains (1) summary
      cl27876
      Location:15996
      Cse1; Cse1
    2. NM_181517.5NP_852658.2  importin-7 isoform 1

      See identical proteins and their annotated locations for NP_852658.2

      Status: VALIDATED

      Source sequence(s)
      AC121995, AC140235
      Consensus CDS
      CCDS40085.1
      UniProtKB/Swiss-Prot
      Q9EPL8
      Related
      ENSMUSP00000081782.4, ENSMUST00000084731.5
      Conserved Domains (2) summary
      COG5656
      Location:15997
      SXM1; Importin, protein involved in nuclear import [Posttranslational modification, protein turnover, chaperones]
      pfam03810
      Location:22101
      IBN_N; Importin-beta N-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      109617522..109655816
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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