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    Pgap2 post-GPI attachment to proteins 2 [ Mus musculus (house mouse) ]

    Gene ID: 233575, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pgap2provided by MGI
    Official Full Name
    post-GPI attachment to proteins 2provided by MGI
    Primary source
    MGI:MGI:2385286
    See related
    Ensembl:ENSMUSG00000030990
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fra; clp; Frag1; clpex; C76649; 1810006G21Rik
    Expression
    Broad expression in genital fat pad adult (RPKM 74.0), testis adult (RPKM 31.4) and 20 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pgap2 in Genome Data Viewer
    Location:
    7; 7 E2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (101859153..101887771)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (102209933..102238564)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (109371588..109386277)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ADP-ribosyltransferase 5 Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 10 Neighboring gene ADP-ribosyltransferase 1 Neighboring gene nucleoporin 98 Neighboring gene ras homolog family member G Neighboring gene stromal interaction molecule 1 Neighboring gene methyltransferase like 6 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Chemically induced (ENU) (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in GPI anchor biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    colocalizes_with Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    post-GPI attachment to proteins factor 2
    Names
    FGF receptor activating protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291358.1NP_001278287.1  post-GPI attachment to proteins factor 2 isoform 1

      See identical proteins and their annotated locations for NP_001278287.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC118592, AK134287, AK152931, BU756950, BY088759
      Consensus CDS
      CCDS40048.1
      UniProtKB/Swiss-Prot
      Q3TQR0
      UniProtKB/TrEMBL
      Q3U6W8
      Related
      ENSMUSP00000114016.2, ENSMUST00000120879.8
      Conserved Domains (1) summary
      pfam10277
      Location:18237
      Frag1; Frag1/DRAM/Sfk1 family
    2. NM_001374617.1NP_001361546.1  post-GPI attachment to proteins factor 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Consensus CDS
      CCDS90290.1
      Conserved Domains (1) summary
      pfam10277
      Location:18241
      Frag1; Frag1/DRAM/Sfk1 family
    3. NM_001382592.1NP_001369521.1  post-GPI attachment to proteins factor 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Related
      ENSMUSP00000033292.8, ENSMUST00000033292.14
      Conserved Domains (1) summary
      pfam10277
      Location:18241
      Frag1; Frag1/DRAM/Sfk1 family
    4. NM_001382593.1NP_001369522.1  post-GPI attachment to proteins factor 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Related
      ENSMUSP00000115590.2, ENSMUST00000138479.8
      Conserved Domains (1) summary
      pfam10277
      Location:18241
      Frag1; Frag1/DRAM/Sfk1 family
    5. NM_001382594.1NP_001369523.1  post-GPI attachment to proteins factor 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:18237
      Frag1; Frag1/DRAM/Sfk1 family
    6. NM_001382595.1NP_001369524.1  post-GPI attachment to proteins factor 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:18241
      Frag1; Frag1/DRAM/Sfk1 family
    7. NM_001382596.1NP_001369525.1  post-GPI attachment to proteins factor 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:18241
      Frag1; Frag1/DRAM/Sfk1 family
    8. NM_001382597.1NP_001369526.1  post-GPI attachment to proteins factor 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:24243
      Frag1; Frag1/DRAM/Sfk1 family
    9. NM_001382598.1NP_001369527.1  post-GPI attachment to proteins factor 2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:24247
      Frag1; Frag1/DRAM/Sfk1 family
    10. NM_001382599.1NP_001369528.1  post-GPI attachment to proteins factor 2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:18203
      Frag1; Frag1/DRAM/Sfk1 family
    11. NM_001382601.1NP_001369530.1  post-GPI attachment to proteins factor 2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:18207
      Frag1; Frag1/DRAM/Sfk1 family
    12. NM_001382603.1NP_001369532.1  post-GPI attachment to proteins factor 2 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:24253
      Frag1; Frag1/DRAM/Sfk1 family
    13. NM_001382604.1NP_001369533.1  post-GPI attachment to proteins factor 2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:18237
      Frag1; Frag1/DRAM/Sfk1 family
    14. NM_001382605.1NP_001369534.1  post-GPI attachment to proteins factor 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:18241
      Frag1; Frag1/DRAM/Sfk1 family
    15. NM_001382607.1NP_001369536.1  post-GPI attachment to proteins factor 2 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:18179
      Frag1; Frag1/DRAM/Sfk1 family
    16. NM_001382608.1NP_001369537.1  post-GPI attachment to proteins factor 2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC118592, AC139579
      Conserved Domains (1) summary
      pfam10277
      Location:18170
      Frag1; Frag1/DRAM/Sfk1 family
    17. NM_145583.3NP_663558.1  post-GPI attachment to proteins factor 2 isoform 1

      See identical proteins and their annotated locations for NP_663558.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AK152931, AK159933, BU756950, BY308583
      Consensus CDS
      CCDS40048.1
      UniProtKB/Swiss-Prot
      Q3TQR0
      UniProtKB/TrEMBL
      Q3U6W8
      Related
      ENSMUSP00000121521.2, ENSMUST00000156529.8
      Conserved Domains (1) summary
      pfam10277
      Location:18237
      Frag1; Frag1/DRAM/Sfk1 family

    RNA

    1. NR_111937.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs at the 5' end and uses an alternate splice junction at the 5' end of an exon compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AK152931, BU756950, BY308583
      Related
      ENSMUST00000150891.8
    2. NR_111938.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs at the 5' end and uses an alternate splice junction at the 5' end of an exon compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AK152931, AK159933, BU756950, BY308583

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      101859153..101887771
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242494.2XP_030098354.1  post-GPI attachment to proteins factor 2 isoform X4

      Conserved Domains (1) summary
      pfam10277
      Location:18237
      Frag1; Frag1/DRAM/Sfk1 family
    2. XM_006507644.5XP_006507707.1  post-GPI attachment to proteins factor 2 isoform X2

      See identical proteins and their annotated locations for XP_006507707.1

      UniProtKB/Swiss-Prot
      Q3TQR0
      Conserved Domains (1) summary
      pfam10277
      Location:18241
      Frag1; Frag1/DRAM/Sfk1 family
    3. XM_036152997.1XP_036008890.1  post-GPI attachment to proteins factor 2 isoform X4

      Conserved Domains (1) summary
      pfam10277
      Location:18237
      Frag1; Frag1/DRAM/Sfk1 family
    4. XM_006507641.5XP_006507704.1  post-GPI attachment to proteins factor 2 isoform X1

      Conserved Domains (1) summary
      pfam10277
      Location:24247
      Frag1; Frag1/DRAM/Sfk1 family
    5. XM_036152996.1XP_036008889.1  post-GPI attachment to proteins factor 2 isoform X2

      Conserved Domains (1) summary
      pfam10277
      Location:18241
      Frag1; Frag1/DRAM/Sfk1 family
    6. XM_036152998.1XP_036008891.1  post-GPI attachment to proteins factor 2 isoform X4

      Conserved Domains (1) summary
      pfam10277
      Location:18237
      Frag1; Frag1/DRAM/Sfk1 family
    7. XM_036152999.1XP_036008892.1  post-GPI attachment to proteins factor 2 isoform X4

      Conserved Domains (1) summary
      pfam10277
      Location:18237
      Frag1; Frag1/DRAM/Sfk1 family
    8. XM_006507649.5XP_006507712.1  post-GPI attachment to proteins factor 2 isoform X6

      Conserved Domains (1) summary
      pfam10277
      Location:27204
      Frag1; Frag1/DRAM/Sfk1 family
    9. XM_006507648.4XP_006507711.1  post-GPI attachment to proteins factor 2 isoform X5

      Conserved Domains (1) summary
      pfam10277
      Location:27208
      Frag1; Frag1/DRAM/Sfk1 family
    10. XM_030242492.1XP_030098352.1  post-GPI attachment to proteins factor 2 isoform X3

      Conserved Domains (1) summary
      pfam10277
      Location:27239
      Frag1; Frag1/DRAM/Sfk1 family
    11. XM_006507646.3XP_006507709.1  post-GPI attachment to proteins factor 2 isoform X3

      See identical proteins and their annotated locations for XP_006507709.1

      UniProtKB/Swiss-Prot
      Q3TQR0
      UniProtKB/TrEMBL
      A0A0R4J1P4
      Related
      ENSMUSP00000113574.2, ENSMUST00000120119.9
      Conserved Domains (1) summary
      pfam10277
      Location:27239
      Frag1; Frag1/DRAM/Sfk1 family
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