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    Tubgcp5 tubulin, gamma complex associated protein 5 [ Mus musculus (house mouse) ]

    Gene ID: 233276, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tubgcp5provided by MGI
    Official Full Name
    tubulin, gamma complex associated protein 5provided by MGI
    Primary source
    MGI:MGI:2178836
    See related
    Ensembl:ENSMUSG00000033790
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GCP; GCP5; mKIAA1899; B130010C12Rik
    Expression
    Ubiquitous expression in CNS E14 (RPKM 4.1), CNS E11.5 (RPKM 4.1) and 26 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tubgcp5 in Genome Data Viewer
    Location:
    7; 7 B5
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (55443873..55481207)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (55794125..55831459)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (63049518..63086817)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 26482 Neighboring gene sialic acid binding Ig-like lectin H Neighboring gene cytoplasmic FMR1 interacting protein 1 Neighboring gene peroxiredoxin 3 pseudogene Neighboring gene non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC38608

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables gamma-tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to microtubule minus-end binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in microtubule nucleation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in equatorial microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of gamma-tubulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of gamma-tubulin large complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    located_in microtubule organizing center IEA
    Inferred from Electronic Annotation
    more info
     
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    gamma-tubulin complex component 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360873.1NP_001347802.1  gamma-tubulin complex component 5 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC102298, AC160534, AK152033
      Consensus CDS
      CCDS90246.1
      Related
      ENSMUSP00000146111.2, ENSMUST00000205796.2
      Conserved Domains (1) summary
      pfam04130
      Location:273879
      Spc97_Spc98; Spc97 / Spc98 family
    2. NM_001360874.1NP_001347803.1  gamma-tubulin complex component 5 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC102298, AC160534
      Conserved Domains (1) summary
      pfam04130
      Location:1659
      Spc97_Spc98; Spc97 / Spc98 family
    3. NM_146190.3NP_666302.2  gamma-tubulin complex component 5 isoform 1

      See identical proteins and their annotated locations for NP_666302.2

      Status: VALIDATED

      Source sequence(s)
      AC160534, AI608079, AK044887, AK051326, BB859898
      Consensus CDS
      CCDS21314.1
      UniProtKB/Swiss-Prot
      Q8BKN5
      Related
      ENSMUSP00000032627.4, ENSMUST00000032627.5
      Conserved Domains (1) summary
      pfam04130
      Location:273942
      Spc97_Spc98; Spc97 / Spc98 family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      55443873..55481207
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540835.5XP_006540898.2  gamma-tubulin complex component 5 isoform X1

      Conserved Domains (1) summary
      cl37603
      Location:271581
      GCP_N_terminal; Gamma tubulin complex component N-terminal

    RNA

    1. XR_882029.4 RNA Sequence

    2. XR_003946456.2 RNA Sequence

      Related
      ENSMUST00000206191.2
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