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    Hnrnpul1 heterogeneous nuclear ribonucleoprotein U-like 1 [ Mus musculus (house mouse) ]

    Gene ID: 232989, updated on 23-Jun-2021

    Summary

    Official Symbol
    Hnrnpul1provided by MGI
    Official Full Name
    heterogeneous nuclear ribonucleoprotein U-like 1provided by MGI
    Primary source
    MGI:MGI:2443517
    See related
    Ensembl:ENSMUSG00000040725
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hn; Hnr; E1BA; E1B-A; E1BAP5; E1B-AP5; Hnrnpul; Hnrpul1; E130317O14Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 34.0), testis adult (RPKM 32.4) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Hnrnpul1 in Genome Data Viewer
    Location:
    7; 7 A3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (25420586..25455695, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (25721161..25756268, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (26507055..26539739, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene transforming growth factor, beta 1 Neighboring gene coiled-coil domain containing 97 Neighboring gene AXL receptor tyrosine kinase Neighboring gene predicted gene, 29763 Neighboring gene cytochrome P450, family 2, subfamily s, polypeptide 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC36621, MGC78330

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in response to virus IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    heterogeneous nuclear ribonucleoprotein U-like protein 1
    Names
    EIB-55kDa associated protein 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360789.1NP_001347718.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorer N-terminus, compared to isoform 1.
      Source sequence(s)
      AK087545, AK143666, AK155604, BY482198, CD804713
      Consensus CDS
      CCDS90188.1
      Related
      ENSMUSP00000037268.9, ENSMUST00000043765.14
      Conserved Domains (2) summary
      cd12884
      Location:112289
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      pfam13671
      Location:324469
      AAA_33; AAA domain
    2. NM_144922.3NP_659171.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_659171.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AK087545, AK143666, AK155604, BY482198, CD804713
      Consensus CDS
      CCDS20995.1
      UniProtKB/Swiss-Prot
      Q8VDM6
      Related
      ENSMUSP00000146263.2, ENSMUST00000206832.2
      Conserved Domains (4) summary
      smart00513
      Location:337
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam13671
      Location:424569
      AAA_33; AAA domain
      cd12884
      Location:212389
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      cl17190
      Location:424562
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    3. NM_178089.3NP_835190.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform 2

      See identical proteins and their annotated locations for NP_835190.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks several exons and contains an alternale 3' terminal exon, resulting in novel 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK042090, AK143666, AK155604, AW494828
      Consensus CDS
      CCDS39841.1
      UniProtKB/Swiss-Prot
      Q8VDM6
      Related
      ENSMUSP00000104038.2, ENSMUST00000108401.3
      Conserved Domains (2) summary
      smart00513
      Location:337
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd12884
      Location:212337
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      25420586..25455695 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539856.4XP_006539919.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006539919.1

      UniProtKB/Swiss-Prot
      Q8VDM6
      Conserved Domains (2) summary
      cd12884
      Location:112289
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      pfam13671
      Location:324469
      AAA_33; AAA domain
    2. XM_036152949.1XP_036008842.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1

      Conserved Domains (2) summary
      cd12884
      Location:112289
      SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1
      pfam13671
      Location:324469
      AAA_33; AAA domain
    3. XM_036152950.1XP_036008843.1  heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X2

      Conserved Domains (1) summary
      pfam13671
      Location:1144
      AAA_33; AAA domain

    RNA

    1. XR_004934071.1 RNA Sequence

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