Ppp1r37 protein phosphatase 1, regulatory subunit 37 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ppp1r37provided by MGI
Official Full Name: protein phosphatase 1, regulatory subunit 37provided by MGI
Primary source: MGI:MGI:2687042
See related: Ensembl:ENSMUSG00000051403 AllianceGenome:MGI:2687042
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm158; Lrrc68
Summary: Predicted to enable protein phosphatase inhibitor activity. Orthologous to human PPP1R37 (protein phosphatase 1 regulatory subunit 37). [provided by Alliance of Genome Resources, Jul 2025]
Expression: Ubiquitous expression in colon adult (RPKM 69.8), adrenal adult (RPKM 50.9) and 28 other tissues See more
Orthologs: all
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Genomic context

Location:: 7 A3; 7 9.93 cM

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (19264725..19298628, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (19530800..19564704, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:235610

G42666 (e-PCR)
- UniSTS:94566

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein phosphatase inhibitor activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: protein phosphatase 1 regulatory subunit 37

Names: leucine rich repeat containing 68; leucine-rich repeat-containing protein 68

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199149.3 → NP_954600.1 protein phosphatase 1 regulatory subunit 37

See identical proteins and their annotated locations for NP_954600.1

Status: PROVISIONAL

Source sequence(s)

AC149052

Consensus CDS

CCDS20906.1

UniProtKB/Swiss-Prot

Q8BKR5

Related

ENSMUSP00000060233.9, ENSMUST00000058444.10

Conserved Domains (3) summary

COG4886
Location:250 → 455

LRR; Leucine-rich repeat (LRR) protein [Transcription]

cd00116
Location:117 → 435

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

sd00033
Location:170 → 198

LRR_RI; leucine-rich repeat [structural motif]