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    Leng8 leukocyte receptor cluster (LRC) member 8 [ Mus musculus (house mouse) ]

    Gene ID: 232798, updated on 28-Oct-2024

    Summary

    Official Symbol
    Leng8provided by MGI
    Official Full Name
    leukocyte receptor cluster (LRC) member 8provided by MGI
    Primary source
    MGI:MGI:2142195
    See related
    Ensembl:ENSMUSG00000035545 AllianceGenome:MGI:2142195
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be active in nucleus. Is expressed in central nervous system; intestine; liver; lung; and retina. Orthologous to human LENG8 (leukocyte receptor cluster member 8). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 180.8), thymus adult (RPKM 168.1) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Leng8 in Genome Data Viewer
    Location:
    7 A1; 7 2.39 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (4140014..4151176)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (4137013..4148177)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9430041J12 gene Neighboring gene predicted gene, 23741 Neighboring gene STARR-seq mESC enhancer starr_17919 Neighboring gene RIKEN cDNA D030047H15 gene Neighboring gene tweety family member 1 Neighboring gene STARR-positive B cell enhancer ABC_E8149 Neighboring gene STARR-seq mESC enhancer starr_17920 Neighboring gene CDC42 effector protein 5 Neighboring gene leukocyte receptor cluster (LRC) member 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    leukocyte receptor cluster member 8 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374609.1NP_001361538.1  leukocyte receptor cluster member 8 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
      Consensus CDS
      CCDS90150.1
      UniProtKB/TrEMBL
      D3YWS8
      Conserved Domains (2) summary
      PRK10263
      Location:113362
      PRK10263; DNA translocase FtsK; Provisional
      cl24019
      Location:568780
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family
    2. NM_001421713.1NP_001408642.1  leukocyte receptor cluster member 8 homolog isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    3. NM_001421715.1NP_001408644.1  leukocyte receptor cluster member 8 homolog isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    4. NM_001421716.1NP_001408645.1  leukocyte receptor cluster member 8 homolog isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    5. NM_001421717.1NP_001408646.1  leukocyte receptor cluster member 8 homolog isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    6. NM_001421718.1NP_001408647.1  leukocyte receptor cluster member 8 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
      UniProtKB/TrEMBL
      D3YWS8
      Related
      ENSMUSP00000112428.2, ENSMUST00000121270.8
    7. NM_001421719.1NP_001408648.1  leukocyte receptor cluster member 8 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
      UniProtKB/TrEMBL
      D3YWS8
    8. NM_001421720.1NP_001408649.1  leukocyte receptor cluster member 8 homolog isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    9. NM_001421721.1NP_001408650.1  leukocyte receptor cluster member 8 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
      UniProtKB/Swiss-Prot
      Q3TCN4, Q8C3P0, Q8CBY3, Q8CGB8
    10. NM_001421722.1NP_001408651.1  leukocyte receptor cluster member 8 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
      UniProtKB/Swiss-Prot
      Q3TCN4, Q8C3P0, Q8CBY3, Q8CGB8
    11. NM_001421723.1NP_001408652.1  leukocyte receptor cluster member 8 homolog isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    12. NM_001421724.1NP_001408653.1  leukocyte receptor cluster member 8 homolog isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    13. NM_001421725.1NP_001408654.1  leukocyte receptor cluster member 8 homolog isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    14. NM_001421726.1NP_001408655.1  leukocyte receptor cluster member 8 homolog isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
      Related
      ENSMUST00000127723.8
    15. NM_001421727.1NP_001408656.1  leukocyte receptor cluster member 8 homolog isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    16. NM_001421728.1NP_001408657.1  leukocyte receptor cluster member 8 homolog isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
      Related
      ENSMUSP00000113223.2, ENSMUST00000117274.8
    17. NM_001421729.1NP_001408658.1  leukocyte receptor cluster member 8 homolog isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
    18. NM_172736.4NP_766324.1  leukocyte receptor cluster member 8 homolog isoform 2

      See identical proteins and their annotated locations for NP_766324.1

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496
      Consensus CDS
      CCDS20731.1
      UniProtKB/Swiss-Prot
      Q3TCN4, Q8C3P0, Q8CBY3, Q8CGB8
      Related
      ENSMUSP00000046465.7, ENSMUST00000037472.13
      Conserved Domains (3) summary
      PRK10263
      Location:113362
      PRK10263; DNA translocase FtsK; Provisional
      PRK14086
      Location:114234
      dnaA; chromosomal replication initiator protein DnaA
      cl24019
      Location:568749
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family

    RNA

    1. NR_185324.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC101941, AC110496

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      4140014..4151176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152936.1XP_036008829.1  leukocyte receptor cluster member 8 homolog isoform X4

      Conserved Domains (1) summary
      cl24019
      Location:548762
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family
    2. XM_036152938.1XP_036008831.1  leukocyte receptor cluster member 8 homolog isoform X5

      Conserved Domains (1) summary
      cl24019
      Location:531745
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family
    3. XM_036152935.1XP_036008828.1  leukocyte receptor cluster member 8 homolog isoform X4

      Conserved Domains (1) summary
      cl24019
      Location:548762
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family
    4. XM_036152934.1XP_036008827.1  leukocyte receptor cluster member 8 homolog isoform X2

      Conserved Domains (2) summary
      PRK10263
      Location:113399
      PRK10263; DNA translocase FtsK; Provisional
      cl24019
      Location:585766
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family