Format

Send to:

Choose Destination
    • Showing Current items.

    Paip2b poly(A) binding protein interacting protein 2B [ Mus musculus (house mouse) ]

    Gene ID: 232164, updated on 23-Jun-2021

    Summary

    Official Symbol
    Paip2bprovided by MGI
    Official Full Name
    poly(A) binding protein interacting protein 2Bprovided by MGI
    Primary source
    MGI:MGI:2386865
    See related
    Ensembl:ENSMUSG00000045896
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in CNS E18 (RPKM 21.3), CNS E14 (RPKM 18.2) and 26 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Paip2b in Genome Data Viewer
    Location:
    6; 6 C3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (83783040..83808723, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (83806058..83831741, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (83756052..83781735, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene predicted gene, 53176 Neighboring gene N-acetylglucosamine kinase Neighboring gene predicted gene, 23014 Neighboring gene ribosomal protein L18 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Clone Names

    • MGC27648, MGC49717

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables poly(A) binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables translation repressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation repressor activity, mRNA regulatory element binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of translation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in negative regulation of translational initiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    polyadenylate-binding protein-interacting protein 2B
    Names
    PABP-interacting protein 2B
    PAIP-2B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146169.2NP_666281.2  polyadenylate-binding protein-interacting protein 2B

      See identical proteins and their annotated locations for NP_666281.2

      Status: VALIDATED

      Source sequence(s)
      AK173114, BY262990, CK381272
      Consensus CDS
      CCDS20287.1
      UniProtKB/Swiss-Prot
      Q91W45
      UniProtKB/TrEMBL
      A0A158RFV3
      Related
      ENSMUSP00000050404.9, ENSMUST00000058383.9
      Conserved Domains (1) summary
      pfam07145
      Location:119135
      PAM2; Ataxin-2 C-terminal region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      83783040..83808723 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center