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    Mob1a MOB kinase activator 1A [ Mus musculus (house mouse) ]

    Gene ID: 232157, updated on 22-Aug-2021

    Summary

    Official Symbol
    Mob1aprovided by MGI
    Official Full Name
    MOB kinase activator 1Aprovided by MGI
    Primary source
    MGI:MGI:2442631
    See related
    Ensembl:ENSMUSG00000043131
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MOB1; MOB4B; Mobk1; Mobkl; Mobk1b; Mobkl1b; 4022402H07Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 24.7), bladder adult (RPKM 21.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Mob1a in Genome Data Viewer
    Location:
    6; 6 C3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (83303016..83319794)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (83326034..83342812)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (83276033..83290943)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 4, sodium bicarbonate cotransporter, member 5 Neighboring gene methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase Neighboring gene bolA-like 3 (E. coli) Neighboring gene tet methylcytosine dioxygenase 3 Neighboring gene microRNA 6374

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC6884

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in hippo signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in hippo signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    MOB kinase activator 1A
    Names
    MOB1, Mps One Binder kinase activator-like 1B
    mob1 homolog 1B
    mps one binder kinase activator-like 1B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145571.2NP_663546.1  MOB kinase activator 1A

      See identical proteins and their annotated locations for NP_663546.1

      Status: PROVISIONAL

      Source sequence(s)
      AK172205
      Consensus CDS
      CCDS39533.1
      UniProtKB/Swiss-Prot
      Q921Y0
      Related
      ENSMUSP00000054452.5, ENSMUST00000055261.11
      Conserved Domains (1) summary
      pfam03637
      Location:33204
      Mob1_phocein; Mob1/phocein family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      83303016..83319794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505969.4XP_006506032.1  MOB kinase activator 1A isoform X1

      See identical proteins and their annotated locations for XP_006506032.1

      Conserved Domains (1) summary
      pfam03637
      Location:32203
      Mob1_phocein; Mob1/phocein family
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