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    Jazf1 JAZF zinc finger 1 [ Mus musculus (house mouse) ]

    Gene ID: 231986, updated on 14-Sep-2021

    Summary

    Official Symbol
    Jazf1provided by MGI
    Official Full Name
    JAZF zinc finger 1provided by MGI
    Primary source
    MGI:MGI:2141450
    See related
    Ensembl:ENSMUSG00000063568
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Jaz; Tip; Jaz1; Tip27; AI591476; C820002C15
    Expression
    Biased expression in testis adult (RPKM 14.8), CNS E18 (RPKM 12.6) and 13 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Jazf1 in Genome Data Viewer
    Location:
    6 B3; 6 25.74 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (52745050..53045615, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (52768065..53068624, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (52718062..53018618, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L24 pseudogene Neighboring gene Tax1 (human T cell leukemia virus type I) binding protein 1 Neighboring gene predicted gene, 52904 Neighboring gene predicted gene, 52903 Neighboring gene predicted gene, 33219 Neighboring gene dynactin subunit 5 pseudogene Neighboring gene predicted gene, 33097 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene quinolinate phosphoribosyltransferase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of transcription repressor complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    juxtaposed with another zinc finger protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168277.1NP_001161749.1  juxtaposed with another zinc finger protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001161749.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AC107317, AC117212, AK050474
      UniProtKB/Swiss-Prot
      Q80ZQ5
      Conserved Domains (1) summary
      COG5189
      Location:105166
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    2. NM_173406.3NP_775582.2  juxtaposed with another zinc finger protein 1 isoform 1

      See identical proteins and their annotated locations for NP_775582.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC117212, AK050474, BY278789
      Consensus CDS
      CCDS20152.1
      UniProtKB/Swiss-Prot
      Q80ZQ5
      Related
      ENSMUSP00000074129.6, ENSMUST00000074541.6
      Conserved Domains (1) summary
      COG5189
      Location:169230
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      52745050..53045615 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505943.5XP_006506006.1  juxtaposed with another zinc finger protein 1 isoform X1

      Conserved Domains (1) summary
      COG5189
      Location:142203
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    2. XM_011241295.2XP_011239597.1  juxtaposed with another zinc finger protein 1 isoform X2

      See identical proteins and their annotated locations for XP_011239597.1

      UniProtKB/Swiss-Prot
      Q80ZQ5
      Conserved Domains (1) summary
      COG5189
      Location:105166
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    3. XM_036166037.1XP_036021930.1  juxtaposed with another zinc finger protein 1 isoform X2

      Conserved Domains (1) summary
      COG5189
      Location:105166
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    4. XM_036166036.1XP_036021929.1  juxtaposed with another zinc finger protein 1 isoform X2

      Conserved Domains (1) summary
      COG5189
      Location:105166
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
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