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    Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 231872, updated on 6-May-2021

    Summary

    Official Symbol
    Aimp2provided by MGI
    Official Full Name
    aminoacyl tRNA synthetase complex-interacting multifunctional protein 2provided by MGI
    Primary source
    MGI:MGI:2385237
    See related
    Ensembl:ENSMUSG00000029610
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Jtv; Jtv1; Aimp2(; AA407136; AA407225; Aimp2(p38)
    Expression
    Ubiquitous expression in adrenal adult (RPKM 41.7), liver E14.5 (RPKM 30.1) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Aimp2 in Genome Data Viewer
    Location:
    5; 5 G2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (143839522..143846657, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (143902704..143909839, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (144663573..144670708, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA D130017N08 gene Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 1 Neighboring gene ankyrin repeat domain 61 Neighboring gene PMS1 homolog2, mismatch repair system component Neighboring gene CCZ1 vacuolar protein trafficking and biogenesis associated Neighboring gene uncharacterized LOC118568766 Neighboring gene predicted gene, 24311 Neighboring gene predicted gene, 33427

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC30261, MGC36346, MGC36522, MGC37389

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular adaptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of aminoacyl-tRNA synthetase multienzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of aminoacyl-tRNA synthetase multienzyme complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    part_of aminoacyl-tRNA synthetase multienzyme complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    aminoacyl tRNA synthase complex-interacting multifunctional protein 2
    Names
    ARS interacting multifunctional protein 2
    multisynthase complex auxiliary component p38
    multisynthetase complex auxiliary component p38
    protein JTV-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001172146.1NP_001165617.1  aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform 1

      See identical proteins and their annotated locations for NP_001165617.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BY202241, CF732613, CX566811
      Consensus CDS
      CCDS51692.1
      UniProtKB/Swiss-Prot
      Q8R010
      Related
      ENSMUSP00000031613.5, ENSMUST00000031613.11
      Conserved Domains (2) summary
      cd03200
      Location:214309
      GST_C_AIMP2; Glutathione S-transferase C-terminal-like, alpha helical domain of Aminoacyl tRNA synthetase complex-Interacting Multifunctional Protein 2
      pfam16780
      Location:133
      AIMP2_LysRS_bd; AIMP2 lysyl-tRNA synthetase binding domain
    2. NM_146165.2NP_666277.1  aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform 2

      See identical proteins and their annotated locations for NP_666277.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment near the N-terminus, compared to isoform 1.
      Source sequence(s)
      BY202241, CJ051555, CX566811
      Consensus CDS
      CCDS39374.1
      UniProtKB/TrEMBL
      Q8R3V2
      Related
      ENSMUSP00000098052.3, ENSMUST00000100483.3
      Conserved Domains (1) summary
      cd03200
      Location:174269
      GST_C_AIMP2; Glutathione S-transferase C-terminal-like, alpha helical domain of Aminoacyl tRNA synthetase complex-Interacting Multifunctional Protein 2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      143839522..143846657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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