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    Mepce methylphosphate capping enzyme [ Mus musculus (house mouse) ]

    Gene ID: 231803, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mepceprovided by MGI
    Official Full Name
    methylphosphate capping enzymeprovided by MGI
    Primary source
    MGI:MGI:106477
    See related
    Ensembl:ENSMUSG00000029726
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bcdi; Bcdin3; D5Wsu46; D5Wsu46e
    Expression
    Ubiquitous expression in testis adult (RPKM 32.4), thymus adult (RPKM 24.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Mepce in Genome Data Viewer
    Location:
    5 G2; 5 76.7 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (137780168..137784963, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (137781906..137786701, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (138223134..138227929, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene TSC22 domain family, member 4 Neighboring gene protein phosphatase 1, regulatory subunit 35 Neighboring gene zinc finger, CW type with PWWP domain 1 Neighboring gene paired immunoglobin-like type 2 receptor alpha Neighboring gene paired immunoglobin-like type 2 receptor beta 1 Neighboring gene predicted gene, 36551

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC28888, MGC30590

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 7SK snRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables O-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA 5'-methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables S-adenosylmethionine-dependent methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables snRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of 7SK snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    7SK snRNA methylphosphate capping enzyme
    Names
    bin3, bicoid-interacting 3, homolog
    NP_659162.3
    XP_017176362.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144913.3NP_659162.3  7SK snRNA methylphosphate capping enzyme

      See identical proteins and their annotated locations for NP_659162.3

      Status: VALIDATED

      Source sequence(s)
      AC125063, AK139731, BF323293
      Consensus CDS
      CCDS39337.1
      UniProtKB/Swiss-Prot
      Q8K3A9
      Related
      ENSMUSP00000031740.10, ENSMUST00000031740.16
      Conserved Domains (2) summary
      cd02440
      Location:423593
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
      pfam06859
      Location:552660
      Bin3; Bicoid-interacting protein 3 (Bin3)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      137780168..137784963 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320873.1XP_017176362.1  7SK snRNA methylphosphate capping enzyme isoform X1

      Conserved Domains (2) summary
      cd02440
      Location:423593
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
      pfam06859
      Location:552650
      Bin3; Bicoid-interacting protein 3 (Bin3)
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