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    Naa25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit [ Mus musculus (house mouse) ]

    Gene ID: 231713, updated on 14-Sep-2021

    Summary

    Official Symbol
    Naa25provided by MGI
    Official Full Name
    N(alpha)-acetyltransferase 25, NatB auxiliary subunitprovided by MGI
    Primary source
    MGI:MGI:2442563
    See related
    Ensembl:ENSMUSG00000042719
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mdm20; AI450868; A630046C11; 4833422K13Rik; C330023M02Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 10.4), whole brain E14.5 (RPKM 8.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Naa25 in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (121535977..121580612)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (121397914..121442549)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (121847991..121890122)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene HECT domain E3 ubiquitin protein ligase 4 Neighboring gene predicted gene, 24671 Neighboring gene TRAF type zinc finger domain containing 1 Neighboring gene predicted gene, 42020 Neighboring gene endoplasmic reticulum protein 29 Neighboring gene transmembrane protein 116 Neighboring gene mitogen-activated protein kinase 3 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (3) 
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to peptide alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in N-terminal peptidyl-methionine acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of NatB complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 25, NatB auxiliary subunit
    Names
    N-terminal acetyltransferase B complex subunit MDM20
    N-terminal acetyltransferase B complex subunit NAA25
    mitochondrial distribution and morphology protein 20
    natB complex subunit MDM20

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172722.4NP_766310.2  N-alpha-acetyltransferase 25, NatB auxiliary subunit

      See identical proteins and their annotated locations for NP_766310.2

      Status: VALIDATED

      Source sequence(s)
      AC129215, AK049325, AK051815, AK076483, BX521975, CF742186
      Consensus CDS
      CCDS19633.1
      UniProtKB/Swiss-Prot
      Q8BWZ3
      UniProtKB/TrEMBL
      B2RQV1
      Related
      ENSMUSP00000038977.9, ENSMUST00000042163.15
      Conserved Domains (2) summary
      sd00006
      Location:4773
      TPR; TPR repeat [structural motif]
      pfam09797
      Location:263655
      NatB_MDM20; N-acetyltransferase B complex (NatB) non catalytic subunit

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      121535977..121580612
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248198.3XP_011246500.1  N-alpha-acetyltransferase 25, NatB auxiliary subunit isoform X1

      Conserved Domains (3) summary
      TIGR02917
      Location:2185
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:1945
      TPR; TPR repeat [structural motif]
      pfam09797
      Location:236630
      NatB_MDM20; N-acetyltransferase B complex (NatB) non catalytic subunit

    RNA

    1. XR_001784683.2 RNA Sequence

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