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    Kmt2c lysine (K)-specific methyltransferase 2C [ Mus musculus (house mouse) ]

    Gene ID: 231051, updated on 2-Oct-2018

    Summary

    Official Symbol
    Kmt2cprovided by MGI
    Official Full Name
    lysine (K)-specific methyltransferase 2Cprovided by MGI
    Primary source
    MGI:MGI:2444959
    See related
    Ensembl:ENSMUSG00000038056 Vega:OTTMUSG00000037000
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HALR; Mll3; E330008K23Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 7.3), whole brain E14.5 (RPKM 6.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Kmt2c in Genome Data Viewer
    Location:
    5; 5 A3-B1
    Exon count:
    62
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (25271794..25498818, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (24777612..25004601, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 11 Neighboring gene heat shock protein 1 (chaperonin 10), pseudogene 3 Neighboring gene sperm associated antigen 7 pseudogene Neighboring gene RIKEN cDNA 4831440E17 gene Neighboring gene chaperonin containing TCP1, subunit 8 (theta)-like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1506

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone methyltransferase activity (H3-K4 specific) IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone methyltransferase activity (H3-K4 specific) ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    histone-lysine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    eyelid development in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    histone methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    methylation IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of fibroblast proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    single fertilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    MLL3/4 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    MLL3/4 complex ISO
    Inferred from Sequence Orthology
    more info
     
    histone methyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    histone-lysine N-methyltransferase 2C
    Names
    histone-lysine N-methyltransferase MLL3
    myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
    NP_001074852.1
    XP_006535745.1
    XP_006535746.1
    XP_006535748.1
    XP_006535749.1
    XP_006535751.1
    XP_006535752.1
    XP_006535753.1
    XP_006535755.1
    XP_006535756.1
    XP_006535757.1
    XP_006535759.1
    XP_006535760.1
    XP_006535761.1
    XP_006535762.1
    XP_006535763.1
    XP_006535764.1
    XP_006535766.1
    XP_011248068.1
    XP_017176308.1
    XP_017176309.1
    XP_017176310.1
    XP_017176311.1
    XP_017176312.1
    XP_017176313.1
    XP_017176314.1
    XP_017176315.1
    XP_017176316.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081383.2NP_001074852.1  histone-lysine N-methyltransferase 2C

      Status: VALIDATED

      Source sequence(s)
      AC116469, AC127319, AC134910
      Consensus CDS
      CCDS39033.1
      UniProtKB/TrEMBL
      F8WI37
      Related
      ENSMUSP00000043874.7, OTTMUSP00000053056, ENSMUST00000045291.13
      Conserved Domains (18) summary
      smart00317
      Location:47654886
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:48884904
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47184904
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10781100
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:342387
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:465516
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10031049
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:389434
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9461002
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10801130
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:246329
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:43954499
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:45454595
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46014682
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32713562
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16821765
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31753251
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16441695
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      25271794..25498818 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249766.2XP_011248068.1  histone-lysine N-methyltransferase 2C isoform X27

      Conserved Domains (18) summary
      smart00398
      Location:15681621
      HMG; high mobility group
      smart00317
      Location:46164737
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:47394755
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:45564755
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10391061
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:9641010
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10411091
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:42504354
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:44004450
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:44564537
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:31973503
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16081691
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31013177
      SYCE1; Synaptonemal complex central element protein 1
      cl22851
      Location:907963
      PHD_SF; PHD finger superfamily
    2. XM_017320827.1XP_017176316.1  histone-lysine N-methyltransferase 2C isoform X26

    3. XM_006535682.3XP_006535745.1  histone-lysine N-methyltransferase 2C isoform X1

      Conserved Domains (18) summary
      smart00317
      Location:48374958
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49604976
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47904976
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44674571
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:46174667
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46734754
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    4. XM_017320820.1XP_017176309.1  histone-lysine N-methyltransferase 2C isoform X6

    5. XM_006535683.3XP_006535746.1  histone-lysine N-methyltransferase 2C isoform X2

      Conserved Domains (18) summary
      smart00317
      Location:48364957
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49594975
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47894975
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10781100
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:342387
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:465516
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10031049
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:389434
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9461002
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10801130
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:246329
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44664570
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:46164666
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46724753
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32873593
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16981781
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31913267
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16601711
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    6. XM_017320819.1XP_017176308.1  histone-lysine N-methyltransferase 2C isoform X3

    7. XM_006535697.3XP_006535760.1  histone-lysine N-methyltransferase 2C isoform X18

      Conserved Domains (18) summary
      smart00317
      Location:47464867
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:48694885
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:46994885
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10391061
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:9641010
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:907963
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10411091
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:43764480
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:45264576
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:45824663
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:31973503
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16081691
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31013177
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:15701621
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    8. XM_017320824.1XP_017176313.1  histone-lysine N-methyltransferase 2C isoform X17

    9. XM_006535694.3XP_006535757.1  histone-lysine N-methyltransferase 2C isoform X15

      Conserved Domains (18) summary
      smart00317
      Location:47974918
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49204936
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47504936
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10391061
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:9641010
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:907963
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10411091
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44274531
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:45774627
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46334714
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32483554
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16591742
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31523228
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16211672
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    10. XM_006535696.3XP_006535759.1  histone-lysine N-methyltransferase 2C isoform X16

      Conserved Domains (18) summary
      smart00317
      Location:47864907
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49094925
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47394925
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44164520
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:45664616
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46224703
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32373543
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16481731
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31413217
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16101661
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    11. XM_006535689.3XP_006535752.1  histone-lysine N-methyltransferase 2C isoform X10

      Conserved Domains (18) summary
      smart00317
      Location:48214942
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49444960
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47744960
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44514555
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:46014651
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46574738
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32723578
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16831766
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31763252
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16451696
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    12. XM_017320826.1XP_017176315.1  histone-lysine N-methyltransferase 2C isoform X24

    13. XM_006535701.3XP_006535764.1  histone-lysine N-methyltransferase 2C isoform X23

      Conserved Domains (18) summary
      smart00317
      Location:46874808
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:48104826
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:46404826
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:43174421
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:44674517
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:45234604
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    14. XM_017320825.1XP_017176314.1  histone-lysine N-methyltransferase 2C isoform X22

    15. XM_006535699.3XP_006535762.1  histone-lysine N-methyltransferase 2C isoform X20

      Conserved Domains (18) summary
      smart00317
      Location:47104831
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:48334849
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:46634849
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:43404444
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:44904540
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:45464627
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    16. XM_006535700.3XP_006535763.1  histone-lysine N-methyltransferase 2C isoform X21

      Conserved Domains (18) summary
      smart00317
      Location:47074828
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:48304846
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:46474846
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:43414445
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:44914541
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:45474628
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    17. XM_006535698.3XP_006535761.1  histone-lysine N-methyltransferase 2C isoform X19

      Conserved Domains (18) summary
      smart00317
      Location:47114832
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:48344850
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:46644850
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:43414445
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:44914541
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:45474628
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    18. XM_017320823.1XP_017176312.1  histone-lysine N-methyltransferase 2C isoform X13

    19. XM_017320821.1XP_017176310.1  histone-lysine N-methyltransferase 2C isoform X8

    20. XM_006535685.3XP_006535748.1  histone-lysine N-methyltransferase 2C isoform X4

      Conserved Domains (18) summary
      smart00317
      Location:48364957
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49594975
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47894975
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44664570
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:46164666
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46724753
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    21. XM_006535693.3XP_006535756.1  histone-lysine N-methyltransferase 2C isoform X14

      Conserved Domains (18) summary
      smart00317
      Location:48094930
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49324948
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47494948
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44434547
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:45934643
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46494730
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    22. XM_006535692.3XP_006535755.1  histone-lysine N-methyltransferase 2C isoform X12

      Conserved Domains (18) summary
      smart00317
      Location:48134934
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49364952
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47664952
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44434547
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:45934643
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46494730
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    23. XM_017320822.1XP_017176311.1  histone-lysine N-methyltransferase 2C isoform X9

    24. XM_006535686.3XP_006535749.1  histone-lysine N-methyltransferase 2C isoform X5

      Conserved Domains (18) summary
      smart00317
      Location:48364957
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49594975
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47894975
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44664570
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:46164666
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46724753
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    25. XM_006535688.3XP_006535751.1  histone-lysine N-methyltransferase 2C isoform X7

      Conserved Domains (18) summary
      smart00317
      Location:48334954
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49564972
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47734972
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9471003
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44674571
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:46174667
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46734754
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32883594
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31923268
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    26. XM_006535690.3XP_006535753.1  histone-lysine N-methyltransferase 2C isoform X11

      Conserved Domains (18) summary
      smart00317
      Location:48204941
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00508
      Location:49434959
      PostSET; Cysteine-rich motif following a subset of SET domains
      COG2940
      Location:47734959
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      sd00025
      Location:10781100
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:342387
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:465516
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10031049
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:389434
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15596
      Location:9461002
      PHD4_KMT2C; PHD finger 4 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10801130
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:246329
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      cd15697
      Location:44504554
      ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam05964
      Location:46004650
      FYRN; F/Y-rich N-terminus
      pfam05965
      Location:46564737
      FYRC; F/Y rich C-terminus
      pfam07223
      Location:32713577
      DUF1421; Protein of unknown function (DUF1421)
      pfam11176
      Location:16821765
      DUF2962; Protein of unknown function (DUF2962)
      pfam15233
      Location:31753251
      SYCE1; Synaptonemal complex central element protein 1
      cl00082
      Location:16441695
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    27. XM_006535703.2XP_006535766.1  histone-lysine N-methyltransferase 2C isoform X25

      Conserved Domains (10) summary
      sd00025
      Location:10791101
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      cd15509
      Location:343388
      PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
      cd15511
      Location:466517
      PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15513
      Location:10041050
      PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
      cd15594
      Location:390435
      PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15600
      Location:10811131
      PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
      cd15696
      Location:247330
      ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
      pfam11176
      Location:16991782
      DUF2962; Protein of unknown function (DUF2962)
      cl00082
      Location:16611712
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
      cl22851
      Location:9471003
      PHD_SF; PHD finger superfamily

    RNA

    1. XR_001784670.1 RNA Sequence

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