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    Tmem201 transmembrane protein 201 [ Mus musculus (house mouse) ]

    Gene ID: 230917, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tmem201provided by MGI
    Official Full Name
    transmembrane protein 201provided by MGI
    Primary source
    MGI:MGI:1196277
    See related
    Ensembl:ENSMUSG00000044700
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sa; Net5; Samp1; AV028368; D4Ertd429; D4Ertd429e
    Expression
    Ubiquitous expression in ovary adult (RPKM 31.0), adrenal adult (RPKM 24.0) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tmem201 in Genome Data Viewer
    Location:
    4 E2; 4 80.15 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (149799832..149822552, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (149715375..149738072, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (149089493..149112145, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene calsyntenin 1 Neighboring gene phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Neighboring gene microRNA 7023 Neighboring gene solute carrier family 25, member 33 Neighboring gene predicted gene 13073

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • RP23-383I7.1

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables actin filament binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables lamin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables lamin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in centrosome localization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within fibroblast migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in nuclear envelope organization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within nuclear migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in nuclear migration along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein localization to nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    colocalizes_with cortical endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of nuclear inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nuclear membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with spindle pole centrosome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 201
    Names
    spindle-associated membrane protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001284270.1NP_001271199.1  transmembrane protein 201 isoform c

      See identical proteins and their annotated locations for NP_001271199.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (c).
      Source sequence(s)
      AK078532, AK086543, AL626808, BE987169, CA316211, CD353644, CD354653, CJ081115, CX562279
      Consensus CDS
      CCDS71523.1
      UniProtKB/Swiss-Prot
      A2A8U2
      UniProtKB/TrEMBL
      Q8C397
      Related
      ENSMUSP00000101312.3, ENSMUST00000105687.9
      Conserved Domains (2) summary
      pfam09779
      Location:47169
      Ima1_N; Ima1 N-terminal domain
      pfam10476
      Location:192379
      DUF2448; Protein of unknown function C-terminus (DUF2448)
    2. NM_001284273.1NP_001271202.1  transmembrane protein 201 isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) contains alternate 5' and 3' exon structure and initiates translation at a downstream start codon, compared to variant 3. It encodes isoform d, which is shorter and has a distinct C-terminus, compared to isoform c.
      Source sequence(s)
      AK040555, AK079157, AK159041, AL626808
      UniProtKB/Swiss-Prot
      A2A8U2
      UniProtKB/TrEMBL
      Q3TXY3, Q8C9U2
      Conserved Domains (2) summary
      pfam09779
      Location:3125
      Ima1_N; Ima1 N-terminal domain
      pfam10476
      Location:148343
      DUF2448; Protein of unknown function C-terminus (DUF2448)
    3. NM_177672.4NP_808340.2  transmembrane protein 201 isoform b

      See identical proteins and their annotated locations for NP_808340.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate 3' exon structure and lacks several exons in the 3' coding region, compared to variant 3. It encodes isoform b, which is shorter and has a distinct C-terminus, compared to isoform c.
      Source sequence(s)
      AK153631, AL626808, CJ081115
      Consensus CDS
      CCDS18965.1
      UniProtKB/Swiss-Prot
      A2A8U2
      Related
      ENSMUSP00000099497.2, ENSMUST00000103208.2
      Conserved Domains (2) summary
      pfam09779
      Location:47169
      Ima1_N; Ima1 N-terminal domain
      pfam10476
      Location:192387
      DUF2448; Protein of unknown function C-terminus (DUF2448)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      149799832..149822552 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538820.5XP_006538883.1  transmembrane protein 201 isoform X1

      Conserved Domains (2) summary
      pfam09779
      Location:47169
      Ima1_N; Ima1 N-terminal domain
      pfam10476
      Location:192379
      DUF2448; Protein of unknown function C-terminus (DUF2448)
    2. XM_006538822.3XP_006538885.1  transmembrane protein 201 isoform X3

      Conserved Domains (2) summary
      pfam09779
      Location:279
      Ima1_N; Ima1 N-terminal domain
      pfam10476
      Location:102289
      DUF2448; Protein of unknown function C-terminus (DUF2448)
    3. XM_006538821.4XP_006538884.1  transmembrane protein 201 isoform X2

      Conserved Domains (2) summary
      pfam09779
      Location:3125
      Ima1_N; Ima1 N-terminal domain
      pfam10476
      Location:148335
      DUF2448; Protein of unknown function C-terminus (DUF2448)
    4. XM_006538823.5XP_006538886.1  transmembrane protein 201 isoform X4

      Conserved Domains (2) summary
      pfam09779
      Location:47169
      Ima1_N; Ima1 N-terminal domain
      pfam10476
      Location:192379
      DUF2448; Protein of unknown function C-terminus (DUF2448)

    RNA

    1. XR_003954938.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001025106.1: Suppressed sequence

      Description
      NM_001025106.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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