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    Foxj3 forkhead box J3 [ Mus musculus (house mouse) ]

    Gene ID: 230700, updated on 23-Jun-2021

    Summary

    Official Symbol
    Foxj3provided by MGI
    Official Full Name
    forkhead box J3provided by MGI
    Primary source
    MGI:MGI:2443432
    See related
    Ensembl:ENSMUSG00000032998
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fhd6; C330039G02Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 9.4), whole brain E14.5 (RPKM 8.7) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Foxj3 in Genome Data Viewer
    Location:
    4; 4 D2.1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (119396858..119486316)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (119539661..119629119)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (119212293..119301724)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene U6 small nuclear RNA, pseudogene 2 Neighboring gene FSHD region gene 2 family member 1 Neighboring gene guanylate cyclase activator 2a (guanylin) Neighboring gene guanylate cyclase activator 2b (retina)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1041, DKFZp761E2211

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in male meiosis I IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    forkhead box protein J3
    Names
    forkhead domain gene 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290696.1NP_001277625.1  forkhead box protein J3 isoform 2

      See identical proteins and their annotated locations for NP_001277625.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1.
      Source sequence(s)
      AK077346, AK082840, BP763140, CB245622, CJ048244
      Consensus CDS
      CCDS71462.1
      UniProtKB/Swiss-Prot
      Q8BUR3
      Related
      ENSMUSP00000101917.3, ENSMUST00000106310.9
      Conserved Domains (2) summary
      pfam15258
      Location:332404
      FAM222A; Protein family of FAM222A
      cd20024
      Location:78154
      FH_FOXJ2-like; Forkhead (FH) domain found in Forkhead box proteins, FOXJ2, FOXJ3 and similar proteins
    2. NM_001357177.1NP_001344106.1  forkhead box protein J3 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 and 3 encode the same isoform (1).
      Source sequence(s)
      AK077346, AK082840, AK139508, AL645563, BP763140
      Consensus CDS
      CCDS18585.1
      Conserved Domains (3) summary
      COG5025
      Location:54347
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam00250
      Location:78155
      Forkhead; Forkhead domain
      pfam09770
      Location:311434
      PAT1; Topoisomerase II-associated protein PAT1
    3. NM_172699.3NP_766287.1  forkhead box protein J3 isoform 1

      See identical proteins and their annotated locations for NP_766287.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer isoform (1). Variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      AK077346, AK082840, AK139508, BP763140
      Consensus CDS
      CCDS18585.1
      UniProtKB/Swiss-Prot
      Q8BUR3
      Related
      ENSMUSP00000035746.9, ENSMUST00000044564.15
      Conserved Domains (3) summary
      COG5025
      Location:54347
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam00250
      Location:78155
      Forkhead; Forkhead domain
      pfam09770
      Location:311434
      PAT1; Topoisomerase II-associated protein PAT1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      119396858..119486316
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503017.5XP_006503080.1  forkhead box protein J3 isoform X1

      See identical proteins and their annotated locations for XP_006503080.1

      UniProtKB/Swiss-Prot
      Q8BUR3
      Conserved Domains (3) summary
      COG5025
      Location:54347
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam00250
      Location:78155
      Forkhead; Forkhead domain
      pfam09770
      Location:311434
      PAT1; Topoisomerase II-associated protein PAT1
    2. XM_036164038.1XP_036019931.1  forkhead box protein J3 isoform X2

      Conserved Domains (2) summary
      pfam15258
      Location:332404
      FAM222A; Protein family of FAM222A
      cd20024
      Location:78154
      FH_FOXJ2-like; Forkhead (FH) domain found in Forkhead box proteins, FOXJ2, FOXJ3 and similar proteins
    3. XM_036164039.1XP_036019932.1  forkhead box protein J3 isoform X2

      Conserved Domains (2) summary
      pfam15258
      Location:332404
      FAM222A; Protein family of FAM222A
      cd20024
      Location:78154
      FH_FOXJ2-like; Forkhead (FH) domain found in Forkhead box proteins, FOXJ2, FOXJ3 and similar proteins
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