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    Foxj3 forkhead box J3 [ Mus musculus (house mouse) ]

    Gene ID: 230700, updated on 2-Oct-2018

    Summary

    Official Symbol
    Foxj3provided by MGI
    Official Full Name
    forkhead box J3provided by MGI
    Primary source
    MGI:MGI:2443432
    See related
    Ensembl:ENSMUSG00000032998 Vega:OTTMUSG00000009437
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fhd6; C330039G02Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 9.4), whole brain E14.5 (RPKM 8.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Foxj3 in Genome Data Viewer
    Location:
    4; 4 D2.1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (119539661..119629119)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (119212293..119301724)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene U6 small nuclear RNA, pseudogene 2 Neighboring gene FSHD region gene 2 family member 1 Neighboring gene guanylate cyclase activator 2a (guanylin) Neighboring gene guanylate cyclase activator 2b (retina)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1041, DKFZp761E2211

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    forkhead box protein J3
    Names
    forkhead domain gene 6

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290696.1NP_001277625.1  forkhead box protein J3 isoform 2

      See identical proteins and their annotated locations for NP_001277625.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1.
      Source sequence(s)
      AK077346, AK082840, BP763140, CB245622, CJ048244
      Consensus CDS
      CCDS71462.1
      UniProtKB/Swiss-Prot
      Q8BUR3
      Related
      ENSMUSP00000101917.2, OTTMUSP00000009819, ENSMUST00000106310.8, OTTMUST00000021489
      Conserved Domains (1) summary
      pfam00250
      Location:78155
      Forkhead; Forkhead domain
    2. NM_001357177.1NP_001344106.1  forkhead box protein J3 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 and 3 encode the same isoform (1).
      Source sequence(s)
      AK077346, AK082840, AK139508, AL645563, BP763140
      Conserved Domains (2) summary
      pfam00250
      Location:78155
      Forkhead; Forkhead domain
      cl25764
      Location:307434
      PAT1; Topoisomerase II-associated protein PAT1
    3. NM_172699.3NP_766287.1  forkhead box protein J3 isoform 1

      See identical proteins and their annotated locations for NP_766287.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer isoform (1). Variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      AK077346, AK082840, AK139508, BP763140
      Consensus CDS
      CCDS18585.1
      UniProtKB/Swiss-Prot
      Q8BUR3
      Related
      ENSMUSP00000035746.8, OTTMUSP00000009818, ENSMUST00000044564.14, OTTMUST00000021488
      Conserved Domains (2) summary
      pfam00250
      Location:78155
      Forkhead; Forkhead domain
      cl25764
      Location:307434
      PAT1; Topoisomerase II-associated protein PAT1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      119539661..119629119
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503017.3XP_006503080.1  forkhead box protein J3 isoform X1

      See identical proteins and their annotated locations for XP_006503080.1

      UniProtKB/Swiss-Prot
      Q8BUR3
      Conserved Domains (2) summary
      pfam00250
      Location:78155
      Forkhead; Forkhead domain
      cl25764
      Location:307434
      PAT1; Topoisomerase II-associated protein PAT1
    2. XM_017320150.1XP_017175639.1  forkhead box protein J3 isoform X1

      UniProtKB/Swiss-Prot
      Q8BUR3
      Conserved Domains (2) summary
      pfam00250
      Location:78155
      Forkhead; Forkhead domain
      cl25764
      Location:307434
      PAT1; Topoisomerase II-associated protein PAT1
    3. XM_011240497.2XP_011238799.1  forkhead box protein J3 isoform X2

      See identical proteins and their annotated locations for XP_011238799.1

      UniProtKB/Swiss-Prot
      Q8BUR3
      Conserved Domains (1) summary
      pfam00250
      Location:78155
      Forkhead; Forkhead domain
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