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    Ecpas Ecm29 proteasome adaptor and scaffold [ Mus musculus (house mouse) ]

    Gene ID: 230249, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ecpasprovided by MGI
    Official Full Name
    Ecm29 proteasome adaptor and scaffoldprovided by MGI
    Primary source
    MGI:MGI:2140220
    See related
    Ensembl:ENSMUSG00000050812
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI314180; AW558785; BB181316; mKIAA0368
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 5.2), bladder adult (RPKM 5.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ecpas in Genome Data Viewer
    Location:
    4; 4 B3
    Exon count:
    52
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (58797234..58913110, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (58812902..58925597, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene 12579 Neighboring gene olfactory receptor 267 Neighboring gene zinc finger with KRAB and SCAN domains 16 Neighboring gene prostaglandin reductase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0368

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    proteasome binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex scaffold activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    proteasome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin-dependent ERAD pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    COPII-coated ER to Golgi transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    endocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    endosome IEA
    Inferred from Electronic Annotation
    more info
     
    late endosome ISO
    Inferred from Sequence Orthology
    more info
     
    multivesicular body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    proteasome complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    proteasome adapter and scaffold protein ECM29; proteasome-associated protein ECM29 homolog
    Names
    ecm29

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355696.1NP_001342625.1  proteasome adapter and scaffold protein ECM29 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AK030369, AK043020, AK054077, AL806535, AW123771, BC058684, BE648557, BG079097
      Conserved Domains (2) summary
      sd00044
      Location:10851108
      HEAT; HEAT repeat [structural motif]
      pfam13001
      Location:16523
      Ecm29; Proteasome stabilizer
    2. NM_001355697.1NP_001342626.1  proteasome adapter and scaffold protein ECM29 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AK030369, AK043020, AK054077, AL806535, AW123771, BC058684, BE648557, BG079097
      Conserved Domains (2) summary
      sd00044
      Location:10791102
      HEAT; HEAT repeat [structural motif]
      pfam13001
      Location:10517
      Ecm29; Proteasome stabilizer
    3. NM_172381.3NP_759013.2  proteasome adapter and scaffold protein ECM29 isoform 2

      See identical proteins and their annotated locations for NP_759013.2

      Status: VALIDATED

      Source sequence(s)
      AK030369, AK041579, AK054077, AL806535, AW123771, BC058684, BE648557, BG079097
      Consensus CDS
      CCDS18214.1
      UniProtKB/Swiss-Prot
      Q6PDI5
      Related
      ENSMUSP00000099953.3, ENSMUST00000102889.9
      Conserved Domains (2) summary
      pfam13001
      Location:10517
      Ecm29; Proteasome stabilizer
      sd00044
      Location:10791102
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      58797234..58913110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537847.3XP_006537910.1  proteasome-associated protein ECM29 homolog isoform X1

      Conserved Domains (2) summary
      sd00044
      Location:10851108
      HEAT; HEAT repeat [structural motif]
      pfam13001
      Location:16523
      Ecm29; Proteasome stabilizer
    2. XM_006537848.3XP_006537911.1  proteasome-associated protein ECM29 homolog isoform X2

      See identical proteins and their annotated locations for XP_006537911.1

      UniProtKB/Swiss-Prot
      Q6PDI5
      Conserved Domains (2) summary
      sd00044
      Location:10791102
      HEAT; HEAT repeat [structural motif]
      pfam13001
      Location:10517
      Ecm29; Proteasome stabilizer
    3. XM_006537850.3XP_006537913.1  proteasome-associated protein ECM29 homolog isoform X3

      Conserved Domains (2) summary
      pfam13001
      Location:1465
      Ecm29; Proteasome stabilizer
      sd00044
      Location:10271050
      HEAT; HEAT repeat [structural motif]
    4. XM_006537849.3XP_006537912.1  proteasome-associated protein ECM29 homolog isoform X2

      UniProtKB/Swiss-Prot
      Q6PDI5
      Related
      ENSMUSP00000117585.1, ENSMUST00000149301.7
      Conserved Domains (2) summary
      sd00044
      Location:10791102
      HEAT; HEAT repeat [structural motif]
      pfam13001
      Location:10517
      Ecm29; Proteasome stabilizer
    5. XM_011250007.2XP_011248309.1  proteasome-associated protein ECM29 homolog isoform X4

      Conserved Domains (2) summary
      pfam13001
      Location:71349
      Ecm29; Proteasome stabilizer
      sd00044
      Location:911934
      HEAT; HEAT repeat [structural motif]
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