Format

Send to:

Choose Destination
    • Showing Current items.

    Rap1gds1 RAP1, GTP-GDP dissociation stimulator 1 [ Mus musculus (house mouse) ]

    Gene ID: 229877, updated on 14-Aug-2021

    Summary

    Official Symbol
    Rap1gds1provided by MGI
    Official Full Name
    RAP1, GTP-GDP dissociation stimulator 1provided by MGI
    Primary source
    MGI:MGI:2385189
    See related
    Ensembl:ENSMUSG00000028149
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GDS; GDS1; BC011279
    Expression
    Broad expression in frontal lobe adult (RPKM 49.1), cortex adult (RPKM 47.6) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rap1gds1 in Genome Data Viewer
    Location:
    3; 3 H1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (138631658..138781163, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (138925897..139075228, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (138588870..138738163, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930425O10 gene Neighboring gene tetraspanin 5 Neighboring gene predicted gene, 54195 Neighboring gene synaptic nuclear envelope 1 pseudogene Neighboring gene predicted gene 4862 Neighboring gene sperm tail PG rich repeat containing 2 Neighboring gene predicted gene, 24260

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC18981

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    rap1 GTPase-GDP dissociation stimulator 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040690.2NP_001035780.1  rap1 GTPase-GDP dissociation stimulator 1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC110574, AC113307, AC119881, AK160989, AK164159, BB400575
      Consensus CDS
      CCDS51083.1
      UniProtKB/TrEMBL
      E9Q912, Q3TPS9, Q3TU36
      Related
      ENSMUSP00000096173.3, ENSMUST00000098574.9
      Conserved Domains (4) summary
      smart00185
      Location:346389
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:42264
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:91116
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:86117
      Arm; Armadillo/beta-catenin-like repeat
    2. NM_001286759.1NP_001273688.1  rap1 GTPase-GDP dissociation stimulator 1 isoform c

      See identical proteins and their annotated locations for NP_001273688.1

      Status: VALIDATED

      Source sequence(s)
      AC110574, AC113307, AK160989, BB400575
      Consensus CDS
      CCDS80033.1
      UniProtKB/TrEMBL
      Q3TU36
      Related
      ENSMUSP00000143181.2, ENSMUST00000196280.5
      Conserved Domains (2) summary
      cd00020
      Location:317430
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      sd00043
      Location:91116
      ARM; armadillo repeat [structural motif]
    3. NM_001356388.1NP_001343317.1  rap1 GTPase-GDP dissociation stimulator 1 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC110574, AC113307, AC119881
      Conserved Domains (3) summary
      pfam00514
      Location:86117
      Arm; Armadillo/beta-catenin-like repeat
      sd00043
      Location:4471
      ARM; armadillo repeat [structural motif]
      cl26969
      Location:177342
      Vitellogenin_N; Lipoprotein amino terminal region
    4. NM_145544.3NP_663519.2  rap1 GTPase-GDP dissociation stimulator 1 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC110574, AC113307, AC119881
      Consensus CDS
      CCDS51082.1
      UniProtKB/TrEMBL
      E9Q6Q4
      Related
      ENSMUSP00000029796.7, ENSMUST00000029796.11
      Conserved Domains (2) summary
      cd00020
      Location:268381
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      sd00043
      Location:4471
      ARM; armadillo repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      138631658..138781163 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252602.2XP_030108462.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X1

      Conserved Domains (3) summary
      smart00185
      Location:168211
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:173212
      ARM; armadillo repeat [structural motif]
      cl26969
      Location:48213
      Vitellogenin_N; Lipoprotein amino terminal region
    2. XM_036163086.1XP_036018979.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X2

      Conserved Domains (3) summary
      smart00185
      Location:168211
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:179330
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:173212
      ARM; armadillo repeat [structural motif]
    3. XM_006501428.5XP_006501491.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X1

      See identical proteins and their annotated locations for XP_006501491.1

      Conserved Domains (3) summary
      smart00185
      Location:168211
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:173212
      ARM; armadillo repeat [structural motif]
      cl26969
      Location:48213
      Vitellogenin_N; Lipoprotein amino terminal region
    4. XM_006501429.5XP_006501492.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X1

      See identical proteins and their annotated locations for XP_006501492.1

      Conserved Domains (3) summary
      smart00185
      Location:168211
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:173212
      ARM; armadillo repeat [structural motif]
      cl26969
      Location:48213
      Vitellogenin_N; Lipoprotein amino terminal region
    5. XM_036163087.1XP_036018980.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X3

      Conserved Domains (4) summary
      PLN03200
      Location:42264
      PLN03200; cellulose synthase-interactive protein; Provisional
      sd00043
      Location:91116
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:86117
      Arm; Armadillo/beta-catenin-like repeat
      cl26969
      Location:226393
      Vitellogenin_N; Lipoprotein amino terminal region
    6. XM_036163088.1XP_036018981.1  rap1 GTPase-GDP dissociation stimulator 1 isoform X4

      Conserved Domains (3) summary
      sd00043
      Location:4471
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:86117
      Arm; Armadillo/beta-catenin-like repeat
      cl26969
      Location:177344
      Vitellogenin_N; Lipoprotein amino terminal region
    Support Center