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    Slc35a3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3 [ Mus musculus (house mouse) ]

    Gene ID: 229782, updated on 28-Oct-2024

    Summary

    Official Symbol
    Slc35a3provided by MGI
    Official Full Name
    solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3provided by MGI
    Primary source
    MGI:MGI:1917648
    See related
    Ensembl:ENSMUSG00000027957 AllianceGenome:MGI:1917648
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310050P13Rik
    Summary
    Enables UDP-galactose transmembrane transporter activity. Involved in UDP-N-acetylglucosamine transmembrane transport. Predicted to be active in Golgi membrane. Is expressed in several structures, including limb; metanephros; tail; testis; and trunk. Orthologous to human SLC35A3 (solute carrier family 35 member A3). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 5.1), colon adult (RPKM 4.5) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Slc35a3 in Genome Data Viewer
    Location:
    3 G1; 3 50.44 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (116463118..116506366, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (116669469..116712708, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene SAS-6 centriolar assembly protein Neighboring gene STARR-seq mESC enhancer starr_08785 Neighboring gene major facilitator superfamily domain containing 14A Neighboring gene STARR-positive B cell enhancer ABC_E3464 Neighboring gene STARR-seq mESC enhancer starr_08789 Neighboring gene STARR-seq mESC enhancer starr_08790 Neighboring gene microRNA 3473h Neighboring gene predicted gene, 40126 Neighboring gene predicted gene, 54181 Neighboring gene STARR-seq mESC enhancer starr_08794 Neighboring gene amylo-1,6-glucosidase, 4-alpha-glucanotransferase Neighboring gene STARR-positive B cell enhancer ABC_E4582 Neighboring gene predicted gene, 40128

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC36317

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables UDP-galactose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables UDP-galactose transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    UDP-N-acetylglucosamine transporter
    Names
    golgi UDP-GlcNAc transporter

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362374.2NP_001349303.1  UDP-N-acetylglucosamine transporter isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
      Consensus CDS
      CCDS17791.1
      UniProtKB/Swiss-Prot
      Q8BRW7, Q8R1T4
      UniProtKB/TrEMBL
      Q3TTK5
      Related
      ENSMUSP00000112674.2, ENSMUST00000120120.8
      Conserved Domains (1) summary
      pfam04142
      Location:1314
      Nuc_sug_transp; Nucleotide-sugar transporter
    2. NM_001404697.1NP_001391626.1  UDP-N-acetylglucosamine transporter isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
    3. NM_001404698.1NP_001391627.1  UDP-N-acetylglucosamine transporter isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
      UniProtKB/Swiss-Prot
      Q8BRW7, Q8R1T4
    4. NM_001404699.1NP_001391628.1  UDP-N-acetylglucosamine transporter isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
    5. NM_001404700.1NP_001391629.1  UDP-N-acetylglucosamine transporter isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
    6. NM_001404701.1NP_001391630.1  UDP-N-acetylglucosamine transporter isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
    7. NM_001404702.1NP_001391631.1  UDP-N-acetylglucosamine transporter isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
    8. NM_001404703.1NP_001391632.1  UDP-N-acetylglucosamine transporter isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
    9. NM_001404704.1NP_001391633.1  UDP-N-acetylglucosamine transporter isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
    10. NM_144902.5NP_659151.1  UDP-N-acetylglucosamine transporter isoform 1

      See identical proteins and their annotated locations for NP_659151.1

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
      Consensus CDS
      CCDS17791.1
      UniProtKB/Swiss-Prot
      Q8BRW7, Q8R1T4
      UniProtKB/TrEMBL
      Q3TTK5
      Related
      ENSMUSP00000029569.3, ENSMUST00000029569.9
      Conserved Domains (1) summary
      pfam04142
      Location:1314
      Nuc_sug_transp; Nucleotide-sugar transporter

    RNA

    1. NR_175853.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242
    2. NR_175854.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC131038, AC147242

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      116463118..116506366 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163085.1XP_036018978.1  UDP-N-acetylglucosamine transporter isoform X5

      Conserved Domains (1) summary
      pfam04142
      Location:1233
      Nuc_sug_transp; Nucleotide-sugar transporter