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    NT5C2 5'-nucleotidase, cytosolic II [ Homo sapiens (human) ]

    Gene ID: 22978, updated on 17-Jun-2024

    Summary

    Official Symbol
    NT5C2provided by HGNC
    Official Full Name
    5'-nucleotidase, cytosolic IIprovided by HGNC
    Primary source
    HGNC:HGNC:8022
    See related
    Ensembl:ENSG00000076685 MIM:600417; AllianceGenome:HGNC:8022
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GMP; NT5B; PNT5; SPG45; SPG65; cN-II
    Summary
    This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]
    Expression
    Ubiquitous expression in thyroid (RPKM 20.3), esophagus (RPKM 12.5) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See NT5C2 in Genome Data Viewer
    Location:
    10q24.32-q24.33
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (103088017..103193272, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (103974258..104079521, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (104847774..104953029, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene BORCS7-ASMT readthrough (NMD candidate) Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104657816-104658316 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104658317-104658817 Neighboring gene uncharacterized LOC107984265 Neighboring gene arsenite methyltransferase Neighboring gene ribosomal protein L22 pseudogene 17 Neighboring gene Sharpr-MPRA regulatory region 3077 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:104677004-104677690 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:104677691-104678377 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2775 Neighboring gene cyclin and CBS domain divalent metal cation transport mediator 2 Neighboring gene MPRA-validated peak1082 silencer Neighboring gene Sharpr-MPRA regulatory region 2614 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3953 Neighboring gene ribosomal protein S15a pseudogene 29 Neighboring gene MARCKS like 1 pseudogene 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104946667-104947166 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:104946165-104946666 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:104951770-104952458 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:104952459-104953145 Neighboring gene CRISPRi-validated cis-regulatory element chr10.3946 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:104962099-104962305 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:104964236-104964895 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:104964896-104965554 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:104990595-104991592 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:104991593-104992590 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3954 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2777 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3955 Neighboring gene ST13, Hsp70 interacting protein pseudogene 13 Neighboring gene ribulose-5-phosphate-3-epimerase like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Hereditary spastic paraplegia 45
    MedGen: C3888209 OMIM: 613162 GeneReviews: Not available
    Compare labs

    EBI GWAS Catalog

    Description
    A comprehensive family-based replication study of schizophrenia genes.
    EBI GWAS Catalog
    Biological insights from 108 schizophrenia-associated genetic loci.
    EBI GWAS Catalog
    Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
    EBI GWAS Catalog
    Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
    EBI GWAS Catalog
    Genome-wide association study identifies eight loci associated with blood pressure.
    EBI GWAS Catalog
    Genome-wide association study identifies five new schizophrenia loci.
    EBI GWAS Catalog
    Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
    EBI GWAS Catalog
    Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.
    EBI GWAS Catalog
    Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci.
    EBI GWAS Catalog
    Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
    EBI GWAS Catalog
    Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
    EBI GWAS Catalog
    Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
    EBI GWAS Catalog

    HIV-1 interactions

    Replication interactions

    Interaction Pubs
    Knockdown of 5'-nucleotidase, cytosolic II (NT5C2) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables 5'-nucleotidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables 5'-nucleotidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables 5'-nucleotidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables GMP 5'-nucleotidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables IMP 5'-nucleotidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables XMP 5'-nucleosidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleoside phosphotransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    cytosolic purine 5'-nucleotidase
    Names
    5'-nucleotidase (purine), cytosolic type B
    IMP-specific 5'-NT
    cytosolic IMP/GMP-specific 5'-nucleotidase
    cytosolic nucleoside phosphotransferase 5'N
    epididymis secretory sperm binding protein
    high Km 5'-nucleotidase
    spastic paraplegia 45 (autosomal recessive)
    NP_001127845.1
    NP_001338098.1
    NP_001338099.1
    NP_001338100.1
    NP_001338101.1
    NP_001338102.1
    NP_001338103.1
    NP_001338104.1
    NP_001338105.1
    NP_001338106.1
    NP_001338107.1
    NP_001338108.1
    NP_001338109.1
    NP_001338110.1
    NP_001338111.1
    NP_001338112.1
    NP_001338113.1
    NP_001338114.1
    NP_001338115.1
    NP_001338116.1
    NP_001338117.1
    NP_001338118.1
    NP_001338119.1
    NP_001338120.1
    NP_001338121.1
    NP_001338122.1
    NP_001338123.1
    NP_001338124.1
    NP_001338125.1
    NP_001338126.1
    NP_036361.1
    XP_005269694.1
    XP_011537839.1
    XP_016871436.1
    XP_024303669.1
    XP_024303670.1
    XP_024303671.1
    XP_047280800.1
    XP_047280801.1
    XP_047280802.1
    XP_047280803.1
    XP_047280804.1
    XP_047280805.1
    XP_047280806.1
    XP_047280807.1
    XP_047280808.1
    XP_047280809.1
    XP_047280810.1
    XP_047280811.1
    XP_047280812.1
    XP_047280813.1
    XP_047280814.1
    XP_047280815.1
    XP_054221213.1
    XP_054221214.1
    XP_054221215.1
    XP_054221216.1
    XP_054221217.1
    XP_054221218.1
    XP_054221219.1
    XP_054221220.1
    XP_054221221.1
    XP_054221222.1
    XP_054221223.1
    XP_054221224.1
    XP_054221225.1
    XP_054221226.1
    XP_054221227.1
    XP_054221228.1
    XP_054221229.1
    XP_054221230.1
    XP_054221231.1
    XP_054221232.1
    XP_054221233.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_042272.1 RefSeqGene

      Range
      5001..110290
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001134373.3NP_001127845.1  cytosolic purine 5'-nucleotidase isoform 1

      See identical proteins and their annotated locations for NP_001127845.1

      Status: REVIEWED

      Source sequence(s)
      AL139817, AL360001
      Consensus CDS
      CCDS7544.1
      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
      Related
      ENSP00000339479.5, ENST00000343289.9
      Conserved Domains (1) summary
      pfam05761
      Location:43488
      5_nucleotid; 5' nucleotidase family
    2. NM_001351169.2NP_001338098.1  cytosolic purine 5'-nucleotidase isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL139817, AL360001
      Consensus CDS
      CCDS7544.1
      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
      Related
      ENSP00000383960.3, ENST00000404739.8
      Conserved Domains (1) summary
      pfam05761
      Location:43488
      5_nucleotid; 5' nucleotidase family
    3. NM_001351170.2NP_001338099.1  cytosolic purine 5'-nucleotidase isoform 2

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DB077941, DB169780
      Consensus CDS
      CCDS91340.1
      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:43496
      5_nucleotid; 5' nucleotidase family
    4. NM_001351171.2NP_001338100.1  cytosolic purine 5'-nucleotidase isoform 2

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BP241199, BU618027, DB077941
      Consensus CDS
      CCDS91340.1
      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:43496
      5_nucleotid; 5' nucleotidase family
    5. NM_001351172.2NP_001338101.1  cytosolic purine 5'-nucleotidase isoform 2

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DB077941, DB164777
      Consensus CDS
      CCDS91340.1
      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
      Related
      ENSP00000502816.1, ENST00000674860.1
      Conserved Domains (1) summary
      pfam05761
      Location:43496
      5_nucleotid; 5' nucleotidase family
    6. NM_001351173.2NP_001338102.1  cytosolic purine 5'-nucleotidase isoform 2

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, BU622015, DB077941, DB164777
      Consensus CDS
      CCDS91340.1
      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:43496
      5_nucleotid; 5' nucleotidase family
    7. NM_001351174.1NP_001338103.1  cytosolic purine 5'-nucleotidase isoform 3

      Status: REVIEWED

      Source sequence(s)
      AK295593, BC001595, BU618027, DC348363
      Consensus CDS
      CCDS91339.1
      UniProtKB/TrEMBL
      A8K6K2
      Related
      ENSP00000502215.1, ENST00000675985.1
      Conserved Domains (1) summary
      pfam05761
      Location:14459
      5_nucleotid; 5' nucleotidase family
    8. NM_001351175.2NP_001338104.1  cytosolic purine 5'-nucleotidase isoform 4

      Status: REVIEWED

      Source sequence(s)
      AK291667, AL360001, BC001595, BU618027, DB164777
      UniProtKB/TrEMBL
      A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:27457
      5_nucleotid; 5' nucleotidase family
    9. NM_001351176.2NP_001338105.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DA724300
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    10. NM_001351177.2NP_001338106.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DA201591, DB169780
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    11. NM_001351178.2NP_001338107.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DA343552, DA408606, DB169780
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    12. NM_001351179.2NP_001338108.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BE936228, BU618027, BU622015, BX648078, DA215274
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    13. NM_001351180.2NP_001338109.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, AL040624, BC001595, BU618027, BX648078, DA493263, DB169780, DB178099
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    14. NM_001351181.2NP_001338110.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DB127914, DB169780, DB443441
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    15. NM_001351182.2NP_001338111.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BE936228, BU618027, BX648078, DA184708, DA724300
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    16. NM_001351183.2NP_001338112.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DA208418, DB169780, DB178099, DB261846
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    17. NM_001351184.2NP_001338113.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BE936228, BU618027, BX648078, DA724300, DB169780
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    18. NM_001351185.2NP_001338114.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BE936228, BU618027, BX648078, DA724300, DB169780
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    19. NM_001351186.2NP_001338115.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BE936228, BU618027, BX648078, DA223605, DA724300, DB169780
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    20. NM_001351187.2NP_001338116.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BE936228, BU618027, BX648078, DA223605, DA408606, DA724300, DB169780
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    21. NM_001351188.2NP_001338117.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BE936228, BU618027, BX648078, DA335453, DB169780
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    22. NM_001351189.2NP_001338118.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BE936228, BU618027, BU622015, BX648078, DA746739, DB178099, DB261846
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    23. NM_001351190.2NP_001338119.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, BU622015, BX648078, DB178099, DB261846, DB287849
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    24. NM_001351191.1NP_001338120.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DA201591, DB127914, DC348363
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    25. NM_001351192.1NP_001338121.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DB097637, DB127914, DC348363
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    26. NM_001351193.1NP_001338122.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BP212875, BU618027, DB097637, DB127914, DC348363
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    27. NM_001351194.2NP_001338123.1  cytosolic purine 5'-nucleotidase isoform 6

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DA208418, DB169780, DB178099, DB261846
      Conserved Domains (1) summary
      cl17687
      Location:1250
      5_nucleotid; 5' nucleotidase family
    28. NM_001351195.2NP_001338124.1  cytosolic purine 5'-nucleotidase isoform 6

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DA184708, DA208418, DB178099, DB261846
      Conserved Domains (1) summary
      cl17687
      Location:1250
      5_nucleotid; 5' nucleotidase family
    29. NM_001351196.2NP_001338125.1  cytosolic purine 5'-nucleotidase isoform 6

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DA208418, DA223605, DB169780, DB178099, DB261846
      Conserved Domains (1) summary
      cl17687
      Location:1250
      5_nucleotid; 5' nucleotidase family
    30. NM_001351197.2NP_001338126.1  cytosolic purine 5'-nucleotidase isoform 5

      Status: REVIEWED

      Source sequence(s)
      AK291667, BC001595, BU618027, DA408606, DA724300, DB169780
      Conserved Domains (1) summary
      cl17687
      Location:1297
      5_nucleotid; 5' nucleotidase family
    31. NM_012229.5NP_036361.1  cytosolic purine 5'-nucleotidase isoform 1

      See identical proteins and their annotated locations for NP_036361.1

      Status: REVIEWED

      Source sequence(s)
      BC001595, BU618027, DA879821
      Consensus CDS
      CCDS7544.1
      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:43488
      5_nucleotid; 5' nucleotidase family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      103088017..103193272 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047424854.1XP_047280810.1  cytosolic purine 5'-nucleotidase isoform X8

      UniProtKB/TrEMBL
      A8K6K2
    2. XM_047424852.1XP_047280808.1  cytosolic purine 5'-nucleotidase isoform X7

      UniProtKB/TrEMBL
      A8K6K2
    3. XM_047424856.1XP_047280812.1  cytosolic purine 5'-nucleotidase isoform X8

      UniProtKB/TrEMBL
      A8K6K2
    4. XM_047424853.1XP_047280809.1  cytosolic purine 5'-nucleotidase isoform X7

      UniProtKB/TrEMBL
      A8K6K2
    5. XM_047424855.1XP_047280811.1  cytosolic purine 5'-nucleotidase isoform X8

      UniProtKB/TrEMBL
      A8K6K2
    6. XM_011539537.2XP_011537839.1  cytosolic purine 5'-nucleotidase isoform X7

      UniProtKB/TrEMBL
      A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:43439
      5_nucleotid; 5' nucleotidase family
    7. XM_047424845.1XP_047280801.1  cytosolic purine 5'-nucleotidase isoform X1

      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
    8. XM_047424847.1XP_047280803.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
    9. XM_024447901.2XP_024303669.1  cytosolic purine 5'-nucleotidase isoform X1

      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:43496
      5_nucleotid; 5' nucleotidase family
    10. XM_047424850.1XP_047280806.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
    11. XM_047424846.1XP_047280802.1  cytosolic purine 5'-nucleotidase isoform X1

      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
    12. XM_047424849.1XP_047280805.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
    13. XM_047424844.1XP_047280800.1  cytosolic purine 5'-nucleotidase isoform X1

      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
    14. XM_047424848.1XP_047280804.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
    15. XM_024447902.2XP_024303670.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:43488
      5_nucleotid; 5' nucleotidase family
    16. XM_005269637.6XP_005269694.1  cytosolic purine 5'-nucleotidase isoform X3

      See identical proteins and their annotated locations for XP_005269694.1

      UniProtKB/TrEMBL
      A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:14467
      5_nucleotid; 5' nucleotidase family
    17. XM_047424851.1XP_047280807.1  cytosolic purine 5'-nucleotidase isoform X5

      UniProtKB/TrEMBL
      A8K6K2
    18. XM_047424857.1XP_047280813.1  cytosolic purine 5'-nucleotidase isoform X9

    19. XM_047424858.1XP_047280814.1  cytosolic purine 5'-nucleotidase isoform X9

    20. XM_017015947.3XP_016871436.1  cytosolic purine 5'-nucleotidase isoform X4

      UniProtKB/TrEMBL
      A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:27465
      5_nucleotid; 5' nucleotidase family
    21. XM_024447903.2XP_024303671.1  cytosolic purine 5'-nucleotidase isoform X6

      UniProtKB/TrEMBL
      A8K6K2
      Conserved Domains (1) summary
      pfam05761
      Location:24452
      5_nucleotid; 5' nucleotidase family
    22. XM_047424859.1XP_047280815.1  cytosolic purine 5'-nucleotidase isoform X9

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      103974258..104079521 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054365254.1XP_054221229.1  cytosolic purine 5'-nucleotidase isoform X8

      UniProtKB/TrEMBL
      A8K6K2
    2. XM_054365252.1XP_054221227.1  cytosolic purine 5'-nucleotidase isoform X7

      UniProtKB/TrEMBL
      A8K6K2
    3. XM_054365256.1XP_054221231.1  cytosolic purine 5'-nucleotidase isoform X8

      UniProtKB/TrEMBL
      A8K6K2
    4. XM_054365253.1XP_054221228.1  cytosolic purine 5'-nucleotidase isoform X7

      UniProtKB/TrEMBL
      A8K6K2
    5. XM_054365255.1XP_054221230.1  cytosolic purine 5'-nucleotidase isoform X8

      UniProtKB/TrEMBL
      A8K6K2
    6. XM_054365251.1XP_054221226.1  cytosolic purine 5'-nucleotidase isoform X7

      UniProtKB/TrEMBL
      A8K6K2
    7. XM_054365240.1XP_054221215.1  cytosolic purine 5'-nucleotidase isoform X1

      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
    8. XM_054365243.1XP_054221218.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
    9. XM_054365239.1XP_054221214.1  cytosolic purine 5'-nucleotidase isoform X1

      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
    10. XM_054365246.1XP_054221221.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
    11. XM_054365241.1XP_054221216.1  cytosolic purine 5'-nucleotidase isoform X1

      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
    12. XM_054365245.1XP_054221220.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
    13. XM_054365238.1XP_054221213.1  cytosolic purine 5'-nucleotidase isoform X1

      UniProtKB/TrEMBL
      A0A6Q8PHP0, A8K6K2
    14. XM_054365244.1XP_054221219.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
    15. XM_054365242.1XP_054221217.1  cytosolic purine 5'-nucleotidase isoform X2

      UniProtKB/Swiss-Prot
      B7Z382, D3DR91, P49902, Q5JUV5
      UniProtKB/TrEMBL
      A0A384MED8, A8K6K2
    16. XM_054365247.1XP_054221222.1  cytosolic purine 5'-nucleotidase isoform X3

      UniProtKB/TrEMBL
      A8K6K2
    17. XM_054365249.1XP_054221224.1  cytosolic purine 5'-nucleotidase isoform X5

      UniProtKB/TrEMBL
      A8K6K2
    18. XM_054365257.1XP_054221232.1  cytosolic purine 5'-nucleotidase isoform X9

    19. XM_054365248.1XP_054221223.1  cytosolic purine 5'-nucleotidase isoform X4

      UniProtKB/TrEMBL
      A8K6K2
    20. XM_054365250.1XP_054221225.1  cytosolic purine 5'-nucleotidase isoform X6

      UniProtKB/TrEMBL
      A8K6K2
    21. XM_054365258.1XP_054221233.1  cytosolic purine 5'-nucleotidase isoform X9