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    Ddx27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [ Mus musculus (house mouse) ]

    Gene ID: 228889, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ddx27provided by MGI
    Official Full Name
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 27provided by MGI
    Primary source
    MGI:MGI:2385884
    See related
    Ensembl:ENSMUSG00000017999
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C86129
    Expression
    Ubiquitous expression in liver E14 (RPKM 22.5), liver E14.5 (RPKM 21.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ddx27 in Genome Data Viewer
    Location:
    2; 2 H3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (167015255..167034950)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (166840813..166860445)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene staufen double-stranded RNA binding protein 1 Neighboring gene GLE1 RNA export mediator pseudogene Neighboring gene zinc finger, NFX1-type containing 1 Neighboring gene small nucleolar RNA, C/D box 12 Neighboring gene zinc finger, NFX1-type containing 1, antisense RNA 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    rRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    chromosome ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    probable ATP-dependent RNA helicase DDX27
    Names
    DEAD box protein 27
    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 27
    RNA-helicase like protein
    NP_694705.2
    XP_006499485.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153065.3NP_694705.2  probable ATP-dependent RNA helicase DDX27

      See identical proteins and their annotated locations for NP_694705.2

      Status: PROVISIONAL

      Source sequence(s)
      AK134274
      Consensus CDS
      CCDS38336.1
      UniProtKB/Swiss-Prot
      Q921N6
      Related
      ENSMUSP00000018143.9, ENSMUST00000018143.15
      Conserved Domains (3) summary
      COG0513
      Location:175640
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
      cd00268
      Location:186390
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
      pfam00271
      Location:415524
      Helicase_C; Helicase conserved C-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      167015255..167034950
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499422.1XP_006499485.1  probable ATP-dependent RNA helicase DDX27 isoform X1

      Conserved Domains (3) summary
      COG0513
      Location:203668
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
      cd00268
      Location:214418
      DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
      pfam00271
      Location:443552
      Helicase_C; Helicase conserved C-terminal domain
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