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    Phf20 PHD finger protein 20 [ Mus musculus (house mouse) ]

    Gene ID: 228829, updated on 23-Jun-2021

    Summary

    Official Symbol
    Phf20provided by MGI
    Official Full Name
    PHD finger protein 20provided by MGI
    Primary source
    MGI:MGI:2444148
    See related
    Ensembl:ENSMUSG00000038116
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6820402O20Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 9.8), CNS E18 (RPKM 9.6) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Phf20 in Genome Data Viewer
    Location:
    2; 2 H1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (156038567..156151873)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (156196647..156309953)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (156022383..156135689)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene nitrogen fixation gene 1 (S. cerevisiae) Neighboring gene reactive oxygen species modulator 1 Neighboring gene RNA binding motif protein 39 Neighboring gene SCAN domain-containing 1 Neighboring gene cyclic nucleotide binding domain containing 2 Neighboring gene predicted gene 14251

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in histone H4-K16 acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H4-K16 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H4-K5 acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H4-K5 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H4-K8 acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H4-K8 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of MLL1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of MLL1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of NSL complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of histone acetyltransferase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    PHD finger protein 20
    Names
    hepatocellular carcinoma-associated antigen 58 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172674.2NP_766262.2  PHD finger protein 20

      See identical proteins and their annotated locations for NP_766262.2

      Status: VALIDATED

      Source sequence(s)
      AK033017, AK035209, AK045309, BC086753, CJ176261
      Consensus CDS
      CCDS38297.1
      UniProtKB/Swiss-Prot
      Q8BLG0
      Related
      ENSMUSP00000043138.9, ENSMUST00000037401.10
      Conserved Domains (5) summary
      cd04508
      Location:90135
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      cd15634
      Location:657700
      PHD_PHF20; PHD finger found in PHD finger protein 20 (PHF20)
      pfam12618
      Location:176259
      DUF3776; Protein of unknown function (DUF3776)
      cl17705
      Location:368
      MBT; mbt repeat
      cl22934
      Location:215313
      DUF1699; Protein of unknown function (DUF1699)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      156038567..156151873
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499338.4XP_006499401.1  PHD finger protein 20 isoform X4

      Conserved Domains (2) summary
      cl17705
      Location:368
      MBT; mbt repeat
      cl22851
      Location:501544
      PHD_SF; PHD finger superfamily
    2. XM_006499339.2XP_006499402.1  PHD finger protein 20 isoform X5

      Conserved Domains (1) summary
      cl22851
      Location:251294
      PHD_SF; PHD finger superfamily
    3. XM_036161523.1XP_036017416.1  PHD finger protein 20 isoform X5

      Conserved Domains (1) summary
      cl22851
      Location:251294
      PHD_SF; PHD finger superfamily
    4. XM_036161511.1XP_036017404.1  PHD finger protein 20 isoform X2

      Conserved Domains (2) summary
      pfam12618
      Location:40114
      DUF3776; Protein of unknown function (DUF3776)
      cl22851
      Location:519562
      PHD_SF; PHD finger superfamily
    5. XM_017317827.2XP_017173316.1  PHD finger protein 20 isoform X1

      Conserved Domains (4) summary
      cd15634
      Location:602645
      PHD_PHF20; PHD finger found in PHD finger protein 20 (PHF20)
      pfam05793
      Location:74259
      TFIIF_alpha; Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
      pfam12618
      Location:123197
      DUF3776; Protein of unknown function (DUF3776)
      cl17705
      Location:368
      MBT; mbt repeat
    6. XM_036161524.1XP_036017417.1  PHD finger protein 20 isoform X5

      Conserved Domains (1) summary
      cl22851
      Location:251294
      PHD_SF; PHD finger superfamily
    7. XM_036161513.1XP_036017406.1  PHD finger protein 20 isoform X2

      Related
      ENSMUST00000152617.8
      Conserved Domains (2) summary
      pfam12618
      Location:40114
      DUF3776; Protein of unknown function (DUF3776)
      cl22851
      Location:519562
      PHD_SF; PHD finger superfamily
    8. XM_036161514.1XP_036017407.1  PHD finger protein 20 isoform X2

      Conserved Domains (2) summary
      pfam12618
      Location:40114
      DUF3776; Protein of unknown function (DUF3776)
      cl22851
      Location:519562
      PHD_SF; PHD finger superfamily
    9. XM_036161515.1XP_036017408.1  PHD finger protein 20 isoform X3

      Conserved Domains (2) summary
      pfam12618
      Location:39113
      DUF3776; Protein of unknown function (DUF3776)
      cl22851
      Location:518561
      PHD_SF; PHD finger superfamily
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