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    Kat14 lysine acetyltransferase 14 [ Mus musculus (house mouse) ]

    Gene ID: 228714, updated on 31-Jan-2019

    Summary

    Official Symbol
    Kat14provided by MGI
    Official Full Name
    lysine acetyltransferase 14provided by MGI
    Primary source
    MGI:MGI:1917264
    See related
    Ensembl:ENSMUSG00000027425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ATAC2; Csrp2bp; AU023459; D2Wsu131e; D2Ertd473e; E430020F17; 2510008M08Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 11.4), placenta adult (RPKM 8.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Kat14 in Genome Data Viewer
    Location:
    2 G1; 2 71.01 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (144369032..144407675)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (144194768..144233411)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase A pseudogene 2_1789.1 Neighboring gene calcium binding and coiled-coil domain 2 pseudogene Neighboring gene PET117 homolog Neighboring gene predicted gene, 46768 Neighboring gene zinc finger protein 133, pseudogene Neighboring gene zinc finger protein pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    histone acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    G2/M transition of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    histone H3 acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    histone acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone acetylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Ada2/Gcn5/Ada3 transcription activator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Ada2/Gcn5/Ada3 transcription activator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Ada2/Gcn5/Ada3 transcription activator complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cysteine-rich protein 2-binding protein
    Names
    ADA2A-containing complex subunit 2
    CRP2-binding partner
    CRP2BP
    CSRP2-binding protein
    cysteine and glycine-rich protein 2 binding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166640.1NP_001160112.1  cysteine-rich protein 2-binding protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an internal segment in the 5' region, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter N-terminus, as compared to isoform 1.
      Source sequence(s)
      AL808123
      Related
      ENSMUSP00000130785.1, ENSMUST00000147747.7
      Conserved Domains (2) summary
      COG0456
      Location:554632
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:552621
      Acetyltransf_1; Acetyltransferase (GNAT) family
    2. NM_181417.3NP_852082.2  cysteine-rich protein 2-binding protein isoform 1

      See identical proteins and their annotated locations for NP_852082.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AL808123
      Consensus CDS
      CCDS16819.1
      UniProtKB/Swiss-Prot
      Q8CID0
      Related
      ENSMUSP00000028911.8, ENSMUST00000028911.14
      Conserved Domains (2) summary
      COG0456
      Location:648760
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:680749
      Acetyltransf_1; Acetyltransferase (GNAT) family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      144369032..144407675
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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