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    Arhgap11a Rho GTPase activating protein 11A [ Mus musculus (house mouse) ]

    Gene ID: 228482, updated on 31-Jan-2019

    Summary

    Official Symbol
    Arhgap11aprovided by MGI
    Official Full Name
    Rho GTPase activating protein 11Aprovided by MGI
    Primary source
    MGI:MGI:2444300
    See related
    Ensembl:ENSMUSG00000041219
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0013; 6530401L14Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 20.9), liver E14 (RPKM 13.4) and 15 other tissues See more
    Orthologs

    Genomic context

    See Arhgap11a in Genome Data Viewer
    Location:
    2; 2 E4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (113831492..113848661, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (113671649..113688818, complement)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene gremlin 1, DAN family BMP antagonist Neighboring gene predicted gene, 46756 Neighboring gene secretogranin V Neighboring gene predicted gene, 30985 Neighboring gene predicted gene, 21596

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    rho GTPase-activating protein 11A
    Names
    GAP (1-12)
    rho-type GTPase-activating protein 11A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181416.3NP_852081.2  rho GTPase-activating protein 11A

      See identical proteins and their annotated locations for NP_852081.2

      Status: VALIDATED

      Source sequence(s)
      AL772405, BC058105, BU052980
      Consensus CDS
      CCDS16562.1
      UniProtKB/Swiss-Prot
      Q80Y19
      Related
      ENSMUSP00000099604.1, ENSMUST00000102545.7
      Conserved Domains (2) summary
      cd04394
      Location:46246
      RhoGAP-ARHGAP11A; RhoGAP-ARHGAP11A: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP11A-like proteins. The mouse homolog of human ArhGAP11A has been detected as a gene exclusively expressed in immature ganglion cells, potentially playing ...
      pfam16609
      Location:371464
      SH3-RhoG_link; SH3-RhoGEF linking unstructured region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      113831492..113848661 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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