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    Epc2 enhancer of polycomb homolog 2 [ Mus musculus (house mouse) ]

    Gene ID: 227867, updated on 31-Jan-2019

    Summary

    Official Symbol
    Epc2provided by MGI
    Official Full Name
    enhancer of polycomb homolog 2provided by MGI
    Primary source
    MGI:MGI:1278321
    See related
    Ensembl:ENSMUSG00000069495
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5830499L14; D2Ertd694e
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 9.1), CNS E14 (RPKM 8.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Epc2 in Genome Data Viewer
    Location:
    2 C1.1; 2 28.62 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (49451486..49551942)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (49307006..49407129)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene methyl-CpG binding domain protein 5 Neighboring gene adaptor protein complex AP-2, mu1 pseudogene Neighboring gene 40S ribosomal protein S3a pseudogene Neighboring gene kinesin family member 5C Neighboring gene predicted gene, 46738 Neighboring gene LY6/PLAUR domain containing 6B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • DKFZp566F2124

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to histone acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    NuA4 histone acetyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
     
    Piccolo NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    enhancer of polycomb homolog 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172663.4NP_766251.3  enhancer of polycomb homolog 2

      See identical proteins and their annotated locations for NP_766251.3

      Status: VALIDATED

      Source sequence(s)
      AK031025, AK141073, AK164886, BB620197, BY253789
      Consensus CDS
      CCDS16023.1
      UniProtKB/Swiss-Prot
      Q8C0I4
      UniProtKB/TrEMBL
      Q3TNY4
      Related
      ENSMUSP00000089758.4, ENSMUST00000092123.10
      Conserved Domains (2) summary
      pfam06752
      Location:578808
      E_Pc_C; Enhancer of Polycomb C-terminus
      pfam10513
      Location:7148
      EPL1; Enhancer of polycomb-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      49451486..49551942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498011.2XP_006498074.1  enhancer of polycomb homolog 2 isoform X1

      Conserved Domains (2) summary
      pfam06752
      Location:514744
      E_Pc_C; Enhancer of Polycomb C-terminus
      pfam10513
      Location:7148
      EPL1; Enhancer of polycomb-like
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