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    Zfr zinc finger RNA binding protein [ Mus musculus (house mouse) ]

    Gene ID: 22763, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zfrprovided by MGI
    Official Full Name
    zinc finger RNA binding proteinprovided by MGI
    Primary source
    MGI:MGI:1341890
    See related
    Ensembl:ENSMUSG00000022201
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C920030H05Rik
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 32.5), cortex adult (RPKM 29.5) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfr in Genome Data Viewer
    Location:
    15; 15 A1
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (12117649..12185535)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (12117563..12185449)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (12047606..12115204)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene 2559 Neighboring gene predicted gene, 34759 Neighboring gene microRNA 1898 Neighboring gene predicted gene 2573 Neighboring gene ribosomal protein S29 pseudogene Neighboring gene myotubularin related protein 12

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC176100

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables double-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables single-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger RNA-binding protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358823.1NP_001345752.1  zinc finger RNA-binding protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AC161269
      Conserved Domains (3) summary
      smart00572
      Location:720974
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00451
      Location:517548
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:520542
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_011767.2NP_035897.2  zinc finger RNA-binding protein isoform 1

      See identical proteins and their annotated locations for NP_035897.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AF071059, AK034963, AK041429, BC058570, BU757317
      Consensus CDS
      CCDS37044.2
      UniProtKB/Swiss-Prot
      O88532
      Related
      ENSMUSP00000118911.2, ENSMUST00000122941.8
      Conserved Domains (4) summary
      smart00572
      Location:7841038
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      PHA03255
      Location:382551
      PHA03255; BDLF3; Provisional
      smart00451
      Location:581612
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:584606
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      12117649..12185535
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520057.2XP_006520120.1  zinc finger RNA-binding protein isoform X1

      Conserved Domains (4) summary
      smart00572
      Location:7921046
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      PHA03255
      Location:390559
      PHA03255; BDLF3; Provisional
      smart00451
      Location:589620
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:341363
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_006520059.3XP_006520122.1  zinc finger RNA-binding protein isoform X5

      Conserved Domains (3) summary
      smart00572
      Location:728982
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00451
      Location:525556
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:528550
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. XM_030248530.1XP_030104390.1  zinc finger RNA-binding protein isoform X3

      Conserved Domains (4) summary
      smart00572
      Location:7721026
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      PHA03255
      Location:370539
      PHA03255; BDLF3; Provisional
      smart00451
      Location:569600
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:321343
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. XM_036159388.1XP_036015281.1  zinc finger RNA-binding protein isoform X6

      Conserved Domains (3) summary
      smart00572
      Location:708962
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      smart00451
      Location:505536
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:508530
      ZF_C2H2; C2H2 Zn finger [structural motif]
    5. XM_006520058.4XP_006520121.1  zinc finger RNA-binding protein isoform X2

      Conserved Domains (4) summary
      smart00572
      Location:7801034
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      PHA03255
      Location:378547
      PHA03255; BDLF3; Provisional
      smart00451
      Location:577608
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:329351
      ZF_C2H2; C2H2 Zn finger [structural motif]
    6. XM_017316588.1XP_017172077.1  zinc finger RNA-binding protein isoform X4

      Conserved Domains (4) summary
      smart00572
      Location:740994
      DZF; domain in DSRM or ZnF_C2H2 domain containing proteins
      PHA03255
      Location:338507
      PHA03255; BDLF3; Provisional
      smart00451
      Location:537568
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:289311
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RNA

    1. XR_001781521.2 RNA Sequence

    2. XR_001781520.3 RNA Sequence

    3. XR_001781522.3 RNA Sequence

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