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    Tubb4b tubulin, beta 4B class IVB [ Mus musculus (house mouse) ]

    Gene ID: 227613, updated on 9-Sep-2018

    Summary

    Official Symbol
    Tubb4bprovided by MGI
    Official Full Name
    tubulin, beta 4B class IVBprovided by MGI
    Primary source
    MGI:MGI:1915472
    See related
    Ensembl:ENSMUSG00000036752 Vega:OTTMUSG00000011806
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tubb2c; Tubb2c1; 4930542G03Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 1044.7), liver E14 (RPKM 404.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tubb4b in Genome Data Viewer
    Location:
    2; 2 A3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (25222158..25224702, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (25077678..25080222, complement)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene negative elongation factor complex member B Neighboring gene sperm tail PG rich repeat containing 3 Neighboring gene family with sequence similarity 166, member A Neighboring gene solute carrier family 34 (sodium phosphate), member 3 Neighboring gene ring finger protein 224

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC6713, MGC28623, MGC101937

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTP binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    double-stranded RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    structural constituent of cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule-based process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule-based process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    myelin sheath IDA
    Inferred from Direct Assay
    more info
    PubMed 
    tubulin complex NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    tubulin beta-4B chain
    Names
    novel tubulin protein
    tubulin beta-2C chain
    tubulin, beta 2C
    tubulin, beta 2c1
    tubulin, beta, 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146116.2NP_666228.1  tubulin beta-4B chain

      See identical proteins and their annotated locations for NP_666228.1

      Status: VALIDATED

      Source sequence(s)
      AK167022, AL732309, CJ309661
      Consensus CDS
      CCDS15753.1
      UniProtKB/Swiss-Prot
      P68372
      Related
      ENSMUSP00000042342.4, OTTMUSP00000012597, ENSMUST00000043584.4, OTTMUST00000027720
      Conserved Domains (1) summary
      PLN00220
      Location:1427
      PLN00220; tubulin beta chain; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      25222158..25224702 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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