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    Slc39a10 solute carrier family 39 (zinc transporter), member 10 [ Mus musculus (house mouse) ]

    Gene ID: 227059, updated on 7-Sep-2021

    Summary

    Official Symbol
    Slc39a10provided by MGI
    Official Full Name
    solute carrier family 39 (zinc transporter), member 10provided by MGI
    Primary source
    MGI:MGI:1914515
    See related
    Ensembl:ENSMUSG00000025986
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zip; Zip10; mKIAA1265; 5430433I10; 2900042E17Rik
    Expression
    Broad expression in cortex adult (RPKM 17.1), frontal lobe adult (RPKM 14.5) and 22 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Slc39a10 in Genome Data Viewer
    Location:
    1; 1 C1.1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (46846704..46964952, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (46807544..46925776, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (46864389..46910354, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene heat shock protein 8 pseudogene Neighboring gene dynein, axonemal, heavy chain 7C Neighboring gene predicted gene, 39638 Neighboring gene DnaJ (Hsp40) homolog, subfamily B, member 6 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables zinc ion transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cellular zinc ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within cellular zinc ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in metal ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of B cell apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of B cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of B cell receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of B cell receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of protein tyrosine phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in zinc ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within zinc ion import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within zinc ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc transporter ZIP10
    Names
    ZIP-10
    solute carrier family 39 member 10
    zrt- and Irt-like protein 10

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356416.1NP_001343345.1  zinc transporter ZIP10 precursor

      Status: VALIDATED

      Source sequence(s)
      AC116452, AC124185
      Consensus CDS
      CCDS14936.1
      Conserved Domains (1) summary
      pfam02535
      Location:406821
      Zip; ZIP Zinc transporter
    2. NM_001356417.1NP_001343346.1  zinc transporter ZIP10 precursor

      Status: VALIDATED

      Source sequence(s)
      AC109276, AC116452, AC124185
      Consensus CDS
      CCDS14936.1
      Conserved Domains (1) summary
      pfam02535
      Location:406821
      Zip; ZIP Zinc transporter
    3. NM_172653.3NP_766241.2  zinc transporter ZIP10 precursor

      See identical proteins and their annotated locations for NP_766241.2

      Status: VALIDATED

      Source sequence(s)
      AC116452, AC124185
      Consensus CDS
      CCDS14936.1
      UniProtKB/Swiss-Prot
      Q6P5F6
      Related
      ENSMUSP00000027131.5, ENSMUST00000027131.6
      Conserved Domains (1) summary
      pfam02535
      Location:406821
      Zip; ZIP Zinc transporter

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      46846704..46964952 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164377.1XP_036020270.1  zinc transporter ZIP10 isoform X2

      Conserved Domains (1) summary
      pfam02535
      Location:406821
      Zip; ZIP Zinc transporter
    2. XM_006495932.3XP_006495995.1  zinc transporter ZIP10 isoform X1

      Conserved Domains (1) summary
      pfam02535
      Location:416831
      Zip; ZIP Zinc transporter
    3. XM_006495933.5XP_006495996.1  zinc transporter ZIP10 isoform X2

      See identical proteins and their annotated locations for XP_006495996.1

      UniProtKB/Swiss-Prot
      Q6P5F6
      Conserved Domains (1) summary
      pfam02535
      Location:406821
      Zip; ZIP Zinc transporter
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