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    Zpr1 ZPR1 zinc finger [ Mus musculus (house mouse) ]

    Gene ID: 22687, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zpr1provided by MGI
    Official Full Name
    ZPR1 zinc fingerprovided by MGI
    Primary source
    MGI:MGI:1330262
    See related
    Ensembl:ENSMUSG00000032078
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ZP; Zfp25; Zfp259; Znf259; AI303781
    Expression
    Ubiquitous expression in testis adult (RPKM 25.2), ovary adult (RPKM 14.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Zpr1 in Genome Data Viewer
    Location:
    9; 9 A5.2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (46184362..46193941)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (46273064..46282643)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (46081147..46090726)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene apolipoprotein A-IV Neighboring gene apolipoprotein A-V Neighboring gene BUD13 homolog Neighboring gene RIKEN cDNA 4931429L15 gene Neighboring gene predicted gene, 39329

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables receptor tyrosine kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables translation initiation factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation initiation factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables translation initiation factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Cajal body organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in Cajal body organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in Cajal body organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in DNA endoreduplication IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in apoptotic process involved in development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in axon development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in axon development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in axon development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell population proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cellular response to epidermal growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in inner cell mass cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of motor neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of RNA splicing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of protein import into nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein import into nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription involved in G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in pre-mRNA catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of myelination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spinal cord development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in trophectodermal cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Cajal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Cajal body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Cajal body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Gemini of coiled bodies IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Gemini of coiled bodies ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in growth cone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perikaryon IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger protein ZPR1
    Names
    zinc finger protein 259

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011752.2NP_035882.1  zinc finger protein ZPR1

      See identical proteins and their annotated locations for NP_035882.1

      Status: VALIDATED

      Source sequence(s)
      AC164105
      Consensus CDS
      CCDS23144.1
      UniProtKB/Swiss-Prot
      Q62384
      Related
      ENSMUSP00000117725.2, ENSMUST00000156440.8
      Conserved Domains (2) summary
      smart00709
      Location:257416
      Zpr1; Duplicated domain in the epidermal growth factor- and elongation factor-1alpha-binding protein Zpr1. Also present in archaeal proteins
      pfam03367
      Location:49206
      zf-ZPR1; ZPR1 zinc-finger domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      46184362..46193941
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_003947860.1 RNA Sequence

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