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    Kctd3 potassium channel tetramerisation domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 226823, updated on 23-Jun-2021

    Summary

    Official Symbol
    Kctd3provided by MGI
    Official Full Name
    potassium channel tetramerisation domain containing 3provided by MGI
    Primary source
    MGI:MGI:2444629
    See related
    Ensembl:ENSMUSG00000026608
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NY-REN; NY-REN-45; 9330185B06; 4930438A20Rik; E330032J19Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 20.9), CNS E14 (RPKM 16.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Kctd3 in Genome Data Viewer
    Location:
    1; 1 H6
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (188703292..188740095, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (188971095..189007898, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (190794977..190831719, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene usherin Neighboring gene predicted gene, 25269 Neighboring gene nuclear encoded tRNA asparagine 3 (anticodon GTT) Neighboring gene predicted gene, 36561 Neighboring gene N-acetylneuraminic acid phosphatase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    BTB/POZ domain-containing protein KCTD3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359576.1NP_001346505.1  BTB/POZ domain-containing protein KCTD3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC129312
      Conserved Domains (1) summary
      pfam02214
      Location:20105
      BTB_2; BTB/POZ domain
    2. NM_001359577.1NP_001346506.1  BTB/POZ domain-containing protein KCTD3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC129312
      Conserved Domains (1) summary
      pfam02214
      Location:20105
      BTB_2; BTB/POZ domain
    3. NM_001359578.1NP_001346507.1  BTB/POZ domain-containing protein KCTD3 isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AC129312
    4. NM_172650.2NP_766238.1  BTB/POZ domain-containing protein KCTD3 isoform 1

      See identical proteins and their annotated locations for NP_766238.1

      Status: VALIDATED

      Source sequence(s)
      AK033491, AK034380, AK087865
      Consensus CDS
      CCDS15608.1
      UniProtKB/Swiss-Prot
      Q8BFX3
      Related
      ENSMUSP00000082821.3, ENSMUST00000085678.8
      Conserved Domains (3) summary
      smart00225
      Location:20114
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam02214
      Location:20105
      BTB_2; BTB/POZ domain
      cl02567
      Location:246448
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RNA

    1. NR_153196.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC129312

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      188703292..188740095 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030253563.2XP_030109423.1  BTB/POZ domain-containing protein KCTD3 isoform X3

    2. XM_036164222.1XP_036020115.1  BTB/POZ domain-containing protein KCTD3 isoform X2

    3. XM_036164219.1XP_036020112.1  BTB/POZ domain-containing protein KCTD3 isoform X1

      Conserved Domains (1) summary
      cl38908
      Location:2153
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    4. XM_017320182.1XP_017175671.1  BTB/POZ domain-containing protein KCTD3 isoform X5

    5. XM_017320175.1XP_017175664.1  BTB/POZ domain-containing protein KCTD3 isoform X4

    RNA

    1. XR_001784135.2 RNA Sequence

    2. XR_373771.4 RNA Sequence

    3. XR_001784133.2 RNA Sequence

    4. XR_001784131.2 RNA Sequence

    5. XR_003954946.1 RNA Sequence

      Related
      ENSMUST00000193143.6
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