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    Zfp148 zinc finger protein 148 [ Mus musculus (house mouse) ]

    Gene ID: 22661, updated on 14-Oct-2018

    Summary

    Official Symbol
    Zfp148provided by MGI
    Official Full Name
    zinc finger protein 148provided by MGI
    Primary source
    MGI:MGI:1332234
    See related
    Ensembl:ENSMUSG00000022811
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BERF-1; BFCOL1; ZBP-89; Znf148; AI480666; AW045217; 2210405J08Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 4.4), cortex adult (RPKM 4.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Zfp148 in Genome Data Viewer
    Location:
    16 B3; 16 23.93 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (33380775..33503903)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (33380861..33503989)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene sorting nexin 4 Neighboring gene RIKEN cDNA 1700007L15 gene Neighboring gene solute carrier family 12 (potassium/chloride transporters), member 8 Neighboring gene heart development protein with EGF-like domains 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase II proximal promoter sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription regulatory region DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    gamete generation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein-containing complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 148
    Names
    G-rich box-binding protein
    beta enolase repressor factor 1
    transcription factor BFCOL1
    transcription factor ZBP-89
    zinc finger DNA-binding protein 89

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358569.1NP_001345498.1  zinc finger protein 148

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC122247, AC127412
      Conserved Domains (3) summary
      sd00017
      Location:173193
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:171193
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:214238
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001358570.1NP_001345499.1  zinc finger protein 148

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC122247, AC127412
      Conserved Domains (3) summary
      sd00017
      Location:173193
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:171193
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:214238
      zf-H2C2_2; Zinc-finger double domain
    3. NM_011749.4NP_035879.1  zinc finger protein 148

      See identical proteins and their annotated locations for NP_035879.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC127412, AK146591, CJ129103, CK634070
      Consensus CDS
      CCDS28130.1
      UniProtKB/Swiss-Prot
      Q61624
      UniProtKB/TrEMBL
      Q3UJ69, Q548L0
      Related
      ENSMUSP00000126338.1, ENSMUST00000165418.8
      Conserved Domains (3) summary
      sd00017
      Location:173193
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:171193
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:214238
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      33380775..33503903
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522098.3XP_006522161.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_006522161.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain
    2. XM_006522103.3XP_006522166.1  zinc finger protein 148 isoform X3

      Related
      ENSMUSP00000156030.1, ENSMUST00000232023.1
      Conserved Domains (3) summary
      sd00017
      Location:131151
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:129151
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:172196
      zf-H2C2_2; Zinc-finger double domain
    3. XM_006522100.3XP_006522163.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_006522163.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain
    4. XM_011245888.2XP_011244190.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_011244190.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain
    5. XM_017316980.1XP_017172469.1  zinc finger protein 148 isoform X2

      UniProtKB/Swiss-Prot
      Q61624
      UniProtKB/TrEMBL
      Q548L0
      Conserved Domains (3) summary
      sd00017
      Location:173193
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:171193
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:214238
      zf-H2C2_2; Zinc-finger double domain
    6. XM_006522099.3XP_006522162.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_006522162.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain
    7. XM_006522101.3XP_006522164.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_006522164.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain
    8. XM_006522102.3XP_006522165.1  zinc finger protein 148 isoform X2

      UniProtKB/Swiss-Prot
      Q61624
      UniProtKB/TrEMBL
      Q548L0
      Related
      ENSMUSP00000087106.6, ENSMUST00000089677.6
      Conserved Domains (3) summary
      sd00017
      Location:173193
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:171193
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:214238
      zf-H2C2_2; Zinc-finger double domain
    9. XM_006522104.3XP_006522167.1  zinc finger protein 148 isoform X4

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