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    Zfp148 zinc finger protein 148 [ Mus musculus (house mouse) ]

    Gene ID: 22661, updated on 26-Sep-2022

    Summary

    Official Symbol
    Zfp148provided by MGI
    Official Full Name
    zinc finger protein 148provided by MGI
    Primary source
    MGI:MGI:1332234
    See related
    Ensembl:ENSMUSG00000022811 AllianceGenome:MGI:1332234
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BERF-1; BFCOL1; ZBP-89; Znf148; 2210405J08Rik
    Summary
    Enables DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within gamete generation and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including cardiovascular system; early conceptus; genitourinary system; gut; and liver and biliary system. Orthologous to human ZNF148 (zinc finger protein 148). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 4.4), cortex adult (RPKM 4.3) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfp148 in Genome Data Viewer
    Location:
    16 B3; 16 23.93 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (33201145..33324273)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (33380775..33503903)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 4 Neighboring gene RIKEN cDNA 1700007L15 gene Neighboring gene solute carrier family 12 (potassium/chloride transporters), member 8 Neighboring gene heart development protein with EGF-like domains 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 148
    Names
    G-rich box-binding protein
    beta enolase repressor factor 1
    transcription factor BFCOL1
    transcription factor ZBP-89
    zinc finger DNA-binding protein 89

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358569.1NP_001345498.1  zinc finger protein 148

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC122247, AC127412
      Consensus CDS
      CCDS28130.1
      UniProtKB/Swiss-Prot
      P97475
      UniProtKB/TrEMBL
      A0A6P7Q7J6, Q548L0
      Related
      ENSMUSP00000087106.7, ENSMUST00000089677.7
      Conserved Domains (3) summary
      sd00017
      Location:173193
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:171193
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:214238
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001358570.1NP_001345499.1  zinc finger protein 148

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC122247, AC127412
      Consensus CDS
      CCDS28130.1
      UniProtKB/Swiss-Prot
      P97475
      UniProtKB/TrEMBL
      A0A6P7Q7J6, Q548L0
      Conserved Domains (3) summary
      sd00017
      Location:173193
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:171193
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:214238
      zf-H2C2_2; Zinc-finger double domain
    3. NM_011749.4NP_035879.1  zinc finger protein 148

      See identical proteins and their annotated locations for NP_035879.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein.
      Source sequence(s)
      AC127412, AK146591, CJ129103, CK634070
      Consensus CDS
      CCDS28130.1
      UniProtKB/Swiss-Prot
      P97475, Q61624
      UniProtKB/TrEMBL
      A0A6P7Q7J6, Q3UJ69, Q548L0
      Related
      ENSMUSP00000126338.2, ENSMUST00000165418.9
      Conserved Domains (3) summary
      sd00017
      Location:173193
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:171193
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:214238
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      33201145..33324273
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522103.5XP_006522166.1  zinc finger protein 148 isoform X3

      UniProtKB/TrEMBL
      A0A338P6K3, A0A6P7QJ61
      Related
      ENSMUSP00000156030.2, ENSMUST00000232023.2
      Conserved Domains (3) summary
      sd00017
      Location:131151
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:129151
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:172196
      zf-H2C2_2; Zinc-finger double domain
    2. XM_006522098.4XP_006522161.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_006522161.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain
    3. XM_036159911.1XP_036015804.1  zinc finger protein 148 isoform X2

      UniProtKB/Swiss-Prot
      P97475
      UniProtKB/TrEMBL
      A0A6P7Q7J6, Q548L0
      Conserved Domains (3) summary
      sd00017
      Location:173193
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:171193
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:214238
      zf-H2C2_2; Zinc-finger double domain
    4. XM_006522099.5XP_006522162.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_006522162.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain
    5. XM_011245888.3XP_011244190.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_011244190.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain
    6. XM_006522100.5XP_006522163.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_006522163.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain
    7. XM_006522101.5XP_006522164.1  zinc finger protein 148 isoform X1

      See identical proteins and their annotated locations for XP_006522164.1

      Conserved Domains (3) summary
      sd00017
      Location:179199
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:177199
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:220244
      zf-H2C2_2; Zinc-finger double domain