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    Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta [ Mus musculus (house mouse) ]

    Gene ID: 22630, updated on 9-Sep-2018

    Summary

    Official Symbol
    Ywhaqprovided by MGI
    Official Full Name
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein thetaprovided by MGI
    Primary source
    MGI:MGI:891963
    See related
    Ensembl:ENSMUSG00000076432 Vega:OTTMUSG00000016335
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    R74690; AA409740; AU021156; 2700028P07Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 170.8), CNS E14 (RPKM 138.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ywhaq in Genome Data Viewer
    Location:
    12; 12 A1.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (21390329..21417436, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (21396190..21423297, complement)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene cleavage and polyadenylation specificity factor 3 Neighboring gene isoamyl acetate-hydrolyzing esterase 1 homolog Neighboring gene a disintegrin and metallopeptidase domain 17 Neighboring gene RIKEN cDNA F630048H11 gene Neighboring gene predicted gene 4419 Neighboring gene predicted gene, 31676

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118161

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    14-3-3 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    ion channel binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    negative regulation of ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    protein targeting IDA
    Inferred from Direct Assay
    more info
    PubMed 
    signal transduction TAS
    Traceable Author Statement
    more info
    PubMed 
    small GTPase mediated signal transduction IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    14-3-3 protein theta
    Names
    14-3-3 protein T-cell
    14-3-3 protein tau
    14-3-3 tau
    14-3-3 theta
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011739.3NP_035869.1  14-3-3 protein theta

      See identical proteins and their annotated locations for NP_035869.1

      Status: PROVISIONAL

      Source sequence(s)
      AC140457
      Consensus CDS
      CCDS25837.1
      UniProtKB/Swiss-Prot
      P68254
      UniProtKB/TrEMBL
      A3KML3
      Related
      ENSMUSP00000100067.1, OTTMUSP00000017541, ENSMUST00000103002.7, OTTMUST00000039250
      Conserved Domains (1) summary
      cd10023
      Location:1234
      14-3-3_theta; 14-3-3 theta/tau (theta in mice, tau in human), an isoform of 14-3-3 protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      21390329..21417436 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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