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    Pprc1 peroxisome proliferative activated receptor, gamma, coactivator-related 1 [ Mus musculus (house mouse) ]

    Gene ID: 226169, updated on 2-Oct-2018

    Summary

    Official Symbol
    Pprc1provided by MGI
    Official Full Name
    peroxisome proliferative activated receptor, gamma, coactivator-related 1provided by MGI
    Primary source
    MGI:MGI:2385096
    See related
    Ensembl:ENSMUSG00000055491 Vega:OTTMUSG00000023305
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PRC; BC013720; mKIAA0595; A930018M19
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 14.9), ovary adult (RPKM 11.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Pprc1 in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (46056525..46072909)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (46131029..46147399)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930505N22 gene Neighboring gene HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 Neighboring gene LIM domain binding 1 Neighboring gene nucleolar and coiled-body phosphoprotein 1 Neighboring gene elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 Neighboring gene paired-like homeodomain transcription factor 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC12121

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear receptor transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    positive regulation of DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Names
    PGC-1-related coactivator

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081214.1NP_001074683.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001074683.1

      Status: VALIDATED

      Source sequence(s)
      AC140233
      Consensus CDS
      CCDS38005.1
      UniProtKB/Swiss-Prot
      Q6NZN1
      Related
      ENSMUSP00000107530.1, OTTMUSP00000027124, ENSMUST00000111899.7, OTTMUST00000056438
      Conserved Domains (1) summary
      cd12624
      Location:15211611
      RRM_PRC; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PRC) and similar proteins
    2. NM_001346801.1NP_001333730.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC140233
      UniProtKB/Swiss-Prot
      Q6NZN1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      46056525..46072909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527008.2XP_006527071.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X3

      Conserved Domains (1) summary
      cd12624
      Location:15211611
      RRM_PRC; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PRC) and similar proteins
    2. XM_017318166.1XP_017173655.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X2

      UniProtKB/Swiss-Prot
      Q6NZN1
    3. XM_006527009.2XP_006527072.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X4

      Conserved Domains (1) summary
      cd12624
      Location:15201610
      RRM_PRC; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PRC) and similar proteins
    4. XM_006527007.2XP_006527070.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X1

      Related
      ENSMUSP00000079389.3, OTTMUSP00000027125, ENSMUST00000062322.10, OTTMUST00000056439
      Conserved Domains (1) summary
      cd12624
      Location:15221612
      RRM_PRC; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PRC) and similar proteins
    5. XM_011247239.1XP_011245541.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X5

      Conserved Domains (1) summary
      cd12624
      Location:15191609
      RRM_PRC; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PRC) and similar proteins
    6. XM_006527010.2XP_006527073.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X6

      Conserved Domains (1) summary
      cd12624
      Location:15171607
      RRM_PRC; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PRC) and similar proteins
    7. XM_006527011.2XP_006527074.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X7

      Conserved Domains (1) summary
      cd12624
      Location:15161606
      RRM_PRC; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PRC) and similar proteins
    8. XM_011247240.2XP_011245542.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X8

      Conserved Domains (1) summary
      cd12624
      Location:14761566
      RRM_PRC; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PRC) and similar proteins
    9. XM_011247241.1XP_011245543.1  peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X9

      Conserved Domains (1) summary
      cd12624
      Location:14051495
      RRM_PRC; RNA recognition motif in peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PRC) and similar proteins

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_145504.1: Suppressed sequence

      Description
      NM_145504.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
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