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    Ric1 RAB6A GEF complex partner 1 [ Mus musculus (house mouse) ]

    Gene ID: 226089, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ric1provided by MGI
    Official Full Name
    RAB6A GEF complex partner 1provided by MGI
    Primary source
    MGI:MGI:1924893
    See related
    Ensembl:ENSMUSG00000038658
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kiaa1432; C030046E11Rik; C130057E09Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 7.7), subcutaneous fat pad adult (RPKM 5.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ric1 in Genome Data Viewer
    Location:
    19; 19 C1
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (29522282..29605921)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (29596772..29680411)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene programmed cell death 1 ligand 2 Neighboring gene RIKEN cDNA A930007I19 gene Neighboring gene endoplasmic reticulum metallopeptidase 1 Neighboring gene predicted gene, 36126

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC159151

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Rab GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Rab GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Rab guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Rab guanyl-nucleotide exchange factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of cellular protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    retrograde transport, endosome to Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RIC1-RGP1 guanyl-nucleotide exchange factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RIC1-RGP1 guanyl-nucleotide exchange factor complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    RAB6A-GEF complex partner protein 1
    Names
    protein RIC1 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081319.1NP_001074788.1  RAB6A-GEF complex partner protein 1

      Status: PROVISIONAL

      Source sequence(s)
      AC093339, AC114578
      Consensus CDS
      CCDS37951.1
      UniProtKB/TrEMBL
      E9QPA1
      Related
      ENSMUSP00000043437.6, ENSMUST00000043610.12
      Conserved Domains (2) summary
      pfam07064
      Location:732989
      RIC1; RIC1
      sd00039
      Location:254304
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      29522282..29605921
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_386464.3 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_177641.2: Suppressed sequence

      Description
      NM_177641.2: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
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