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    Patl1 protein associated with topoisomerase II homolog 1 (yeast) [ Mus musculus (house mouse) ]

    Gene ID: 225929, updated on 23-Jun-2021

    Summary

    Official Symbol
    Patl1provided by MGI
    Official Full Name
    protein associated with topoisomerase II homolog 1 (yeast)provided by MGI
    Primary source
    MGI:MGI:2147679
    See related
    Ensembl:ENSMUSG00000046139
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pat; Pat1b; AV312086
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 13.6), whole brain E14.5 (RPKM 11.1) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Patl1 in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (11889728..11922462)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (11912399..11945096)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (11986889..12019586)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted pseudogene 6365 Neighboring gene olfactory receptor 1420 Neighboring gene predicted gene, 31092 Neighboring gene microRNA 6994 Neighboring gene predicted gene, 22272 Neighboring gene uncharacterized protein C11orf98 homolog pseudogene Neighboring gene oxysterol binding protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • D430024J04

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G-quadruplex RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables poly(G) binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables poly(U) RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables translation repressor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in P-body assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in P-body assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of translation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of CCR4-NOT complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in P-body ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein PAT1 homolog 1
    Names
    PAT1-like protein 1
    protein PAT1 homolog b

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172635.3NP_766223.2  protein PAT1 homolog 1

      See identical proteins and their annotated locations for NP_766223.2

      Status: VALIDATED

      Source sequence(s)
      AC124464, AK150301, AK161738, AV316026
      Consensus CDS
      CCDS37924.1
      UniProtKB/Swiss-Prot
      Q3TC46
      Related
      ENSMUSP00000060398.8, ENSMUST00000061618.9
      Conserved Domains (1) summary
      cl22451
      Location:8104
      ASF1_hist_chap; ASF1 like histone chaperone

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      11889728..11922462
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161548.1XP_036017441.1  protein PAT1 homolog 1 isoform X3

      Conserved Domains (2) summary
      pfam09770
      Location:241436
      PAT1; Topoisomerase II-associated protein PAT1
      cl22451
      Location:8104
      ASF1_hist_chap; ASF1 like histone chaperone
    2. XM_030250884.2XP_030106744.1  protein PAT1 homolog 1 isoform X2

      Conserved Domains (1) summary
      pfam09770
      Location:22394
      PAT1; Topoisomerase II-associated protein PAT1
    3. XM_036161547.1XP_036017440.1  protein PAT1 homolog 1 isoform X1

      Conserved Domains (1) summary
      pfam09770
      Location:166538
      PAT1; Topoisomerase II-associated protein PAT1

    RNA

    1. XR_004940138.1 RNA Sequence

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