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    Patl1 protein associated with topoisomerase II homolog 1 (yeast) [ Mus musculus (house mouse) ]

    Gene ID: 225929, updated on 31-Jan-2019

    Summary

    Official Symbol
    Patl1provided by MGI
    Official Full Name
    protein associated with topoisomerase II homolog 1 (yeast)provided by MGI
    Primary source
    MGI:MGI:2147679
    See related
    Ensembl:ENSMUSG00000046139
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pat1b; AV312086
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 13.6), whole brain E14.5 (RPKM 11.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Patl1 in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (11912399..11945096)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (11986889..12019586)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene predicted pseudogene 6365 Neighboring gene olfactory receptor 1420 Neighboring gene predicted gene, 31092 Neighboring gene microRNA 6994 Neighboring gene uncharacterized protein C11orf98 homolog pseudogene Neighboring gene oxysterol binding protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • D430024J04

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-quadruplex RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    poly(G) binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    poly(U) RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    translation repressor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    cytoplasmic mRNA processing body assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasmic mRNA processing body assembly ISO
    Inferred from Sequence Orthology
    more info
     
    deadenylation-dependent decapping of nuclear-transcribed mRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    deadenylation-dependent decapping of nuclear-transcribed mRNA ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of translation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    colocalizes_with CCR4-NOT complex ISO
    Inferred from Sequence Orthology
    more info
     
    P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    P-body ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein PAT1 homolog 1
    Names
    PAT1-like protein 1
    protein PAT1 homolog b

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172635.3NP_766223.2  protein PAT1 homolog 1

      See identical proteins and their annotated locations for NP_766223.2

      Status: VALIDATED

      Source sequence(s)
      AC124464, AK150301, AK161738, AV316026
      Consensus CDS
      CCDS37924.1
      UniProtKB/Swiss-Prot
      Q3TC46
      Related
      ENSMUSP00000060398.7, ENSMUST00000061618.7
      Conserved Domains (1) summary
      cl22451
      Location:8104
      ASF1_hist_chap; ASF1 like histone chaperone

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      11912399..11945096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526947.2XP_006527010.1  protein PAT1 homolog 1 isoform X1

      Conserved Domains (1) summary
      cl21556
      Location:275322
      DUF2184; Uncharacterized protein conserved in bacteria (DUF2184)
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