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    Cep76 centrosomal protein 76 [ Mus musculus (house mouse) ]

    Gene ID: 225659, updated on 26-Sep-2022

    Summary

    Official Symbol
    Cep76provided by MGI
    Official Full Name
    centrosomal protein 76provided by MGI
    Primary source
    MGI:MGI:1923401
    See related
    Ensembl:ENSMUSG00000073542 AllianceGenome:MGI:1923401
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9630013E05; 6230425F05Rik
    Summary
    Predicted to be involved in regulation of centriole replication. Predicted to be located in centriole and centrosome. Predicted to be part of protein-containing complex. Is expressed in ductus deferens; prostate gland; and testis. Orthologous to human CEP76 (centrosomal protein 76). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in liver E14 (RPKM 12.6), liver E14.5 (RPKM 11.9) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Cep76 in Genome Data Viewer
    Location:
    18; 18 E1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (67750034..67774425, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (67616964..67641355, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene PRELI domain containing 3A Neighboring gene spire type actin nucleation factor 1 Neighboring gene predicted gene, 17669 Neighboring gene proteasome (prosome, macropain) assembly chaperone 2 Neighboring gene protein tyrosine phosphatase, non-receptor type 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of centriole replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of centriole replication ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    centrosomal protein of 76 kDa

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081073.2NP_001074542.1  centrosomal protein of 76 kDa isoform 1

      See identical proteins and their annotated locations for NP_001074542.1

      Status: VALIDATED

      Source sequence(s)
      AC120410
      Consensus CDS
      CCDS37850.1
      UniProtKB/Swiss-Prot
      Q0VEJ0
      Related
      ENSMUSP00000095149.3, ENSMUST00000097542.4
      Conserved Domains (2) summary
      pfam01841
      Location:365411
      Transglut_core; Transglutaminase-like superfamily
      pfam15627
      Location:101258
      CEP76-C2; CEP76 C2 domain
    2. NM_001357523.1NP_001344452.1  centrosomal protein of 76 kDa isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC120410
      Conserved Domains (2) summary
      pfam01841
      Location:187233
      Transglut_core; Transglutaminase-like superfamily
      pfam15627
      Location:180
      CEP76-C2; CEP76 C2 domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      67750034..67774425 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)