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    Etf1 eukaryotic translation termination factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 225363, updated on 22-Aug-2021

    Summary

    Official Symbol
    Etf1provided by MGI
    Official Full Name
    eukaryotic translation termination factor 1provided by MGI
    Primary source
    MGI:MGI:2385071
    See related
    Ensembl:ENSMUSG00000024360
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ERF; ERF1; SUP4; TB3-1; SUP45L1; AI463371; D6Ertd109; D6Ertd109e
    Expression
    Ubiquitous expression in placenta adult (RPKM 27.4), CNS E11.5 (RPKM 25.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Etf1 in Genome Data Viewer
    Location:
    18; 18 B1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (35035838..35065060, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (34902785..34932008, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (35062439..35091657, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene early growth response 1 Neighboring gene predicted gene, 54018 Neighboring gene heat shock protein 9 Neighboring gene predicted gene, 22200 Neighboring gene predicted gene, 26109

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC18745

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables sequence-specific mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables sequence-specific mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation release factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation release factor activity, codon specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation termination factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of translation release factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    eukaryotic peptide chain release factor subunit 1
    Names
    eukaryotic release factor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144866.3NP_659115.3  eukaryotic peptide chain release factor subunit 1

      See identical proteins and their annotated locations for NP_659115.3

      Status: VALIDATED

      Source sequence(s)
      AC114820, AI844751, AK169345, BY238984
      Consensus CDS
      CCDS29137.1
      UniProtKB/Swiss-Prot
      Q8BWY3
      UniProtKB/TrEMBL
      Q3TF02
      Related
      ENSMUSP00000025218.8, ENSMUST00000025218.8
      Conserved Domains (1) summary
      COG1503
      Location:11419
      eRF1; Peptide chain release factor 1 (eRF1) [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      35035838..35065060 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030250436.2XP_030106296.1  eukaryotic peptide chain release factor subunit 1 isoform X1

      Conserved Domains (1) summary
      COG1503
      Location:1386
      eRF1; Peptide chain release factor 1 (eRF1) [Translation, ribosomal structure and biogenesis]
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