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    Etf1 eukaryotic translation termination factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 225363, updated on 31-Jan-2019

    Summary

    Official Symbol
    Etf1provided by MGI
    Official Full Name
    eukaryotic translation termination factor 1provided by MGI
    Primary source
    MGI:MGI:2385071
    See related
    Ensembl:ENSMUSG00000024360
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ERF; ERF1; TB3-1; SUP45L1; AI463371; D6Ertd109e
    Expression
    Ubiquitous expression in placenta adult (RPKM 27.4), CNS E11.5 (RPKM 25.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Etf1 in Genome Data Viewer
    Location:
    18; 18 B1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (34902785..34932003, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (35062439..35091657, complement)

    Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41689 Neighboring gene early growth response 1 Neighboring gene heat shock protein 9 Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC18745

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    sequence-specific mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sequence-specific mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    translation release factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    translation release factor activity, codon specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    translation termination factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cytoplasmic translational termination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
    Inferred from Electronic Annotation
    more info
     
    protein methylation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    translation IEA
    Inferred from Electronic Annotation
    more info
     
    translational termination ISO
    Inferred from Sequence Orthology
    more info
     
    viral process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    translation release factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    eukaryotic peptide chain release factor subunit 1
    Names
    eukaryotic release factor 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144866.3NP_659115.3  eukaryotic peptide chain release factor subunit 1

      See identical proteins and their annotated locations for NP_659115.3

      Status: VALIDATED

      Source sequence(s)
      AC114820, AI844751, AK169345, BY238984
      Consensus CDS
      CCDS29137.1
      UniProtKB/Swiss-Prot
      Q8BWY3
      UniProtKB/TrEMBL
      Q3TF02
      Related
      ENSMUSP00000025218.7, ENSMUST00000025218.7
      Conserved Domains (1) summary
      COG1503
      Location:11419
      eRF1; Peptide chain release factor 1 (eRF1) [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

      Range
      34902785..34932003 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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