Format

Send to:

Choose Destination
    • Showing Current items.

    Wdr36 WD repeat domain 36 [ Mus musculus (house mouse) ]

    Gene ID: 225348, updated on 23-Jun-2021

    Summary

    Official Symbol
    Wdr36provided by MGI
    Official Full Name
    WD repeat domain 36provided by MGI
    Primary source
    MGI:MGI:1917819
    See related
    Ensembl:ENSMUSG00000038299
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ta-wdrp; 5730444A13Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 8.0), placenta adult (RPKM 7.8) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Wdr36 in Genome Data Viewer
    Location:
    18; 18 B1
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (32970241..33000008)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (32837188..32866955)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (32996879..33026074)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930455D15 gene Neighboring gene predicted gene, 26378 Neighboring gene thymic stromal lymphopoietin Neighboring gene microRNA 6361 Neighboring gene RIKEN cDNA 2310026I22 gene Neighboring gene calcium/calmodulin-dependent protein kinase IV

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC38421

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within regulation of axon extension IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within retina homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of Pwp2p-containing subcomplex of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    WD repeat-containing protein 36

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110015.1NP_001103485.1  WD repeat-containing protein 36 isoform 1

      See identical proteins and their annotated locations for NP_001103485.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest variant and encodes the longest isoform (1).
      Source sequence(s)
      AC140983, AK040339, AK077545
      Consensus CDS
      CCDS50246.1
      UniProtKB/TrEMBL
      Q3TAQ9
      Related
      ENSMUSP00000052465.10, ENSMUST00000053663.11
      Conserved Domains (4) summary
      COG2319
      Location:137612
      WD40; WD40 repeat [General function prediction only]
      pfam04192
      Location:674895
      Utp21; Utp21 specific WD40 associated putative domain
      sd00039
      Location:74107
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:279598
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    2. NM_001110016.1NP_001103486.1  WD repeat-containing protein 36 isoform 2

      See identical proteins and their annotated locations for NP_001103486.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses and alternate splice site in the 3' terminal exon, compared to variant 1, which results in a shorter protein (isoform 2) with a distinct C-terminus when compared to isoform 1.
      Source sequence(s)
      AC140983, AK040339, AK077545, BP767184
      Consensus CDS
      CCDS50245.1
      UniProtKB/TrEMBL
      Q3TA68
      Related
      ENSMUSP00000132189.2, ENSMUST00000166214.9
      Conserved Domains (4) summary
      COG2319
      Location:137612
      WD40; WD40 repeat [General function prediction only]
      pfam04192
      Location:674872
      Utp21; Utp21 specific WD40 associated putative domain
      sd00039
      Location:74107
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:279598
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    3. NM_144863.4NP_659112.2  WD repeat-containing protein 36 isoform 3

      See identical proteins and their annotated locations for NP_659112.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 3' UTR and has multiple 3' coding region differences, compared to variant 1, which result in a shorter protein (isoform 3) with a distinct C-terminus when compared to isoform 1.
      Source sequence(s)
      AC140983, AK045396
      UniProtKB/TrEMBL
      Q8BHI6
      Related
      ENSMUST00000234158.2
      Conserved Domains (3) summary
      COG2319
      Location:98484
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:74107
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:102367
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      32970241..33000008
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525847.4XP_006525910.1  WD repeat-containing protein 36 isoform X1

      Conserved Domains (3) summary
      sd00039
      Location:74107
      7WD40; WD40 repeat [structural motif]
      pfam04192
      Location:674873
      Utp21; Utp21 specific WD40 associated putative domain
      cl29593
      Location:279598
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Support Center