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    Fbxo11 F-box protein 11 [ Mus musculus (house mouse) ]

    Gene ID: 225055, updated on 3-Feb-2019

    Summary

    Official Symbol
    Fbxo11provided by MGI
    Official Full Name
    F-box protein 11provided by MGI
    Primary source
    MGI:MGI:2147134
    See related
    Ensembl:ENSMUSG00000005371
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Jf; C80048
    Expression
    Ubiquitous expression in CNS E14 (RPKM 23.5), whole brain E14.5 (RPKM 20.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Fbxo11 in Genome Data Viewer
    Location:
    17 E4; 17 57.87 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (87990859..88066092, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (88390199..88464625, complement)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41649 Neighboring gene ribosomal protein L36, pseudogene 4 Neighboring gene mutS homolog 6 Neighboring gene predicted gene, 45950 Neighboring gene predicted gene 4832

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Chemically induced (ENU) (2)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC156416

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein-arginine N-methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-protein transferase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cellular protein modification process ISO
    Inferred from Sequence Orthology
    more info
     
    protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    sensory perception of sound IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081034.2NP_001074503.1  F-box only protein 11 isoform 1

      See identical proteins and their annotated locations for NP_001074503.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC087233, AC154673, AI853268, BC055343, BY127063, CA557033, CA749247, CF169182, CF172333, CN533292, CN666984
      Consensus CDS
      CCDS37717.1
      UniProtKB/Swiss-Prot
      Q7TPD1
      Related
      ENSMUSP00000005504.8, ENSMUST00000005504.14
      Conserved Domains (3) summary
      pfam12937
      Location:160203
      F-box-like; F-box-like
      pfam13229
      Location:667812
      Beta_helix; Right handed beta helix region
      cl19744
      Location:853894
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
    2. NM_001348248.1NP_001335177.1  F-box only protein 11 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AC087233, AC154673, BC055343, BY127063, CA557033, CA749247, CF169182, CF172333, CN533292, CN666984
      UniProtKB/Swiss-Prot
      Q7TPD1
      Conserved Domains (3) summary
      pfam12937
      Location:73116
      F-box-like; F-box-like
      pfam13229
      Location:580725
      Beta_helix; Right handed beta helix region
      cl19744
      Location:766807
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      87990859..88066092 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524203.3XP_006524266.3  F-box only protein 11 isoform X1

      Related
      ENSMUSP00000121206.2, ENSMUST00000130379.8
      Conserved Domains (3) summary
      pfam12937
      Location:159202
      F-box-like; F-box-like
      pfam13229
      Location:666811
      Beta_helix; Right handed beta helix region
      cl19744
      Location:852893
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
    2. XM_006524204.3XP_006524267.1  F-box only protein 11 isoform X2

      See identical proteins and their annotated locations for XP_006524267.1

      UniProtKB/Swiss-Prot
      Q7TPD1
      Related
      ENSMUSP00000157024.1, ENSMUST00000235112.1
      Conserved Domains (3) summary
      pfam12937
      Location:73116
      F-box-like; F-box-like
      pfam13229
      Location:580725
      Beta_helix; Right handed beta helix region
      cl19744
      Location:766807
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
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