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    Crb3 crumbs family member 3 [ Mus musculus (house mouse) ]

    Gene ID: 224912, updated on 14-Sep-2021

    Summary

    Official Symbol
    Crb3provided by MGI
    Official Full Name
    crumbs family member 3provided by MGI
    Primary source
    MGI:MGI:2670904
    See related
    Ensembl:ENSMUSG00000044279
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AU015179; AU041752; 5730439B18
    Expression
    Broad expression in duodenum adult (RPKM 28.1), colon adult (RPKM 24.9) and 17 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Crb3 in Genome Data Viewer
    Location:
    17; 17 D
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (57368583..57372920)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (57062201..57065918)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (57201700..57205341)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25, member 41 Neighboring gene solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 Neighboring gene DENN/MADD domain containing 1C Neighboring gene tubulin, beta 4A class IVA

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SH3 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in apical part of cell IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in apical plasma membrane ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of subapical complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347408.1NP_001334337.1  protein crumbs homolog 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      BP769883, CT571247
      Consensus CDS
      CCDS84327.1
      UniProtKB/Swiss-Prot
      Q8QZT4
      Related
      ENSMUSP00000125760.2, ENSMUST00000169543.8
      Conserved Domains (1) summary
      pfam15345
      Location:2109
      TMEM51; Transmembrane protein 51
    2. NM_001359813.1NP_001346742.1  protein crumbs homolog 3 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AK077528, AK167279, BP769883
      Consensus CDS
      CCDS28924.1
      Related
      ENSMUSP00000071729.4, ENSMUST00000071826.10
    3. NM_001359814.1NP_001346743.1  protein crumbs homolog 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      CT571247
      Consensus CDS
      CCDS84327.1
      Conserved Domains (1) summary
      pfam15345
      Location:2109
      TMEM51; Transmembrane protein 51
    4. NM_177638.5NP_808306.1  protein crumbs homolog 3 isoform 1 precursor

      See identical proteins and their annotated locations for NP_808306.1

      Status: VALIDATED

      Source sequence(s)
      CT571247
      Consensus CDS
      CCDS28924.1
      UniProtKB/Swiss-Prot
      Q8QZT4
      Related
      ENSMUSP00000094902.4, ENSMUST00000097299.10

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      57368583..57372920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160561.1XP_036016454.1  protein crumbs homolog 3 isoform X1

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