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    Trerf1 transcriptional regulating factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 224829, updated on 2-Oct-2018

    Summary

    Official Symbol
    Trerf1provided by MGI
    Official Full Name
    transcriptional regulating factor 1provided by MGI
    Primary source
    MGI:MGI:2442086
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RAPA; Trep132; AI429294; Trep-132; B830015H24; 9430096I18Rik
    Expression
    Broad expression in adrenal adult (RPKM 13.0), thymus adult (RPKM 8.8) and 23 other tissues See more
    Orthologs

    Genomic context

    See Trerf1 in Genome Data Viewer
    Location:
    17; 17 C
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (47140942..47359458)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (47277891..47496407)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein L29 pseudogene Neighboring gene predicted gene, 41589 Neighboring gene predicted gene, 36715 Neighboring gene mitochondrial ribosomal protein S10 Neighboring gene guanylate cyclase activator 1B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118525

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription regulatory region DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    histone deacetylase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    transcriptional-regulating factor 1
    Names
    transcriptional regulating protein 132
    zinc finger transcription factor TReP-132

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001097623.2NP_001091092.1  transcriptional-regulating factor 1 isoform 1

      See identical proteins and their annotated locations for NP_001091092.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC112683, BC059215
      UniProtKB/Swiss-Prot
      Q8BXJ2
      Conserved Domains (5) summary
      smart00717
      Location:914959
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      sd00017
      Location:10411063
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01448
      Location:807861
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:915959
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    2. NM_172622.3NP_766210.1  transcriptional-regulating factor 1 isoform 2

      See identical proteins and their annotated locations for NP_766210.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform 2).
      Source sequence(s)
      AC112683, AK042320, AK046822
      UniProtKB/Swiss-Prot
      Q8BXJ2
      Conserved Domains (5) summary
      smart00717
      Location:894939
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      sd00017
      Location:10211043
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01448
      Location:787841
      ELM2; ELM2 domain
      pfam13912
      Location:514534
      zf-C2H2_6; C2H2-type zinc finger
      cl21498
      Location:895939
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      47140942..47359458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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