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    Cip2a cell proliferation regulating inhibitor of protein phosphatase 2A [ Mus musculus (house mouse) ]

    Gene ID: 224171, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cip2aprovided by MGI
    Official Full Name
    cell proliferation regulating inhibitor of protein phosphatase 2Aprovided by MGI
    Primary source
    MGI:MGI:2146335
    See related
    Ensembl:ENSMUSG00000033031
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AA408511; AU018569; Kiaa1524; C330027C09Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 14.8), liver E14 (RPKM 13.4) and 12 other tissues See more
    Orthologs

    Genomic context

    See Cip2a in Genome Data Viewer
    Location:
    16; 16 B5
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (48994188..49019705)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (48994301..49019818)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene resistin like gamma Neighboring gene DAZ interacting protein 3, zinc finger Neighboring gene myosin, heavy chain 15 Neighboring gene RIKEN cDNA 1700026J12 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    positive regulation of neural precursor cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein CIP2A
    Names
    cancerous inhibitor of PP2A
    p90 autoantigen homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172616.2NP_766204.2  protein CIP2A

      See identical proteins and their annotated locations for NP_766204.2

      Status: VALIDATED

      Source sequence(s)
      AK049356, AK160639, AV113368, BY453073
      Consensus CDS
      CCDS49867.1
      UniProtKB/Swiss-Prot
      Q8BWY9
      Related
      ENSMUSP00000044714.5, ENSMUST00000048374.5
      Conserved Domains (3) summary
      COG1340
      Location:631879
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam16046
      Location:675839
      FAM76; FAM76 protein
      cl23720
      Location:810893
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      48994188..49019705
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522091.3XP_006522154.1  protein CIP2A isoform X1

      Conserved Domains (3) summary
      COG1340
      Location:470718
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      pfam16046
      Location:514678
      FAM76; FAM76 protein
      cl23720
      Location:649732
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
    2. XM_006522092.2XP_006522155.1  protein CIP2A isoform X2

      Conserved Domains (2) summary
      pfam16046
      Location:355519
      FAM76; FAM76 protein
      cl23720
      Location:490573
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)
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