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    Golgb1 golgin B1 [ Mus musculus (house mouse) ]

    Gene ID: 224139, updated on 18-Sep-2024

    Summary

    Official Symbol
    Golgb1provided by MGI
    Official Full Name
    golgin B1provided by MGI
    Primary source
    MGI:MGI:1099447
    See related
    Ensembl:ENSMUSG00000034243 AllianceGenome:MGI:1099447
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    628101; Gm6840; mKIAA4151; 4930428L02Rik; 6330407A06Rik; C130074L01Rik; F730017E11Rik
    Summary
    Predicted to be involved in chondrocyte proliferation and protein localization to pericentriolar material. Located in cis-Golgi network. Is expressed in several structures, including embryo endoderm; face; limb; limb bud; and nervous system. Used to study cleft palate. Orthologous to human GOLGB1 (golgin B1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 10.4), placenta adult (RPKM 9.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Golgb1 in Genome Data Viewer
    Location:
    16 B3; 16 26.19 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (36695455..36753447)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (36875093..36933085)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 15 (H+/peptide transporter), member 2 Neighboring gene 60S ribosomal protein L7a pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E764 Neighboring gene ELL associated factor 2 Neighboring gene STARR-positive B cell enhancer ABC_E1185 Neighboring gene STARR-positive B cell enhancer ABC_E10903 Neighboring gene IQ calmodulin-binding motif containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E5541 Neighboring gene STARR-positive B cell enhancer ABC_E99 Neighboring gene RIKEN cDNA 4930565N06 gene Neighboring gene STARR-positive B cell enhancer mm9_chr16:36884785-36885086 Neighboring gene STARR-seq mESC enhancer starr_40776 Neighboring gene STARR-positive B cell enhancer ABC_E8632 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:36932162-36932315 Neighboring gene STARR-positive B cell enhancer ABC_E7446 Neighboring gene STARR-positive B cell enhancer ABC_E4169 Neighboring gene hematopoietic cell specific Lyn substrate 1 Neighboring gene STARR-seq mESC enhancer starr_40777 Neighboring gene F-box protein 40 Neighboring gene STARR-seq mESC enhancer starr_40778

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA4151, MGC183642

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in chondrocyte proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in cis-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cis-Golgi network IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    golgin subfamily B member 1
    Names
    giantin
    golgi autoantigen, golgin subfamily b, macrogolgin 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030035.1NP_084311.1  golgin subfamily B member 1

      See identical proteins and their annotated locations for NP_084311.1

      Status: VALIDATED

      Source sequence(s)
      AC154763
      Consensus CDS
      CCDS49844.1
      UniProtKB/TrEMBL
      B2RWW2, E9PVZ8
      Conserved Domains (3) summary
      COG1196
      Location:18372656
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:11671242
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:13312164
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      36695455..36753447
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522082.3XP_006522145.1  golgin subfamily B member 1 isoform X1

      See identical proteins and their annotated locations for XP_006522145.1

      UniProtKB/TrEMBL
      B2RWW2, E9PVZ8
      Conserved Domains (3) summary
      COG1196
      Location:18372656
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:11671242
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:13312164
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    2. XM_006522084.5XP_006522147.1  golgin subfamily B member 1 isoform X1

      See identical proteins and their annotated locations for XP_006522147.1

      UniProtKB/TrEMBL
      B2RWW2, E9PVZ8
      Related
      ENSMUSP00000045239.9, ENSMUST00000039855.9
      Conserved Domains (3) summary
      COG1196
      Location:18372656
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:11671242
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:13312164
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    3. XM_030249086.2XP_030104946.1  golgin subfamily B member 1 isoform X2

      UniProtKB/TrEMBL
      B2RWW2
      Conserved Domains (4) summary
      COG1196
      Location:18312650
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK00252
      Location:49118
      alaS; alanyl-tRNA synthetase; Reviewed
      PRK12704
      Location:11611236
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:13252158
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    4. XM_030249088.1XP_030104948.1  golgin subfamily B member 1 isoform X4

      UniProtKB/TrEMBL
      B2RWW2, E9QAH1
      Conserved Domains (4) summary
      COG1196
      Location:17962615
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK00252
      Location:49118
      alaS; alanyl-tRNA synthetase; Reviewed
      PRK12704
      Location:11261201
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:12902123
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    5. XM_017316964.2XP_017172453.1  golgin subfamily B member 1 isoform X1

      UniProtKB/TrEMBL
      B2RWW2, E9PVZ8
      Conserved Domains (3) summary
      COG1196
      Location:18372656
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:11671242
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:13312164
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    6. XM_017316963.3XP_017172452.1  golgin subfamily B member 1 isoform X1

      UniProtKB/TrEMBL
      B2RWW2, E9PVZ8
      Conserved Domains (3) summary
      COG1196
      Location:18372656
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:11671242
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:13312164
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    7. XM_017316965.2XP_017172454.1  golgin subfamily B member 1 isoform X3

      UniProtKB/TrEMBL
      B2RWW2
      Conserved Domains (3) summary
      COG1196
      Location:17992618
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:11291204
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:12932126
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    8. XM_030249087.2XP_030104947.1  golgin subfamily B member 1 isoform X4

      UniProtKB/TrEMBL
      B2RWW2, E9QAH1
      Conserved Domains (4) summary
      COG1196
      Location:17962615
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK00252
      Location:49118
      alaS; alanyl-tRNA synthetase; Reviewed
      PRK12704
      Location:11261201
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:12902123
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    9. XM_017316966.2XP_017172455.1  golgin subfamily B member 1 isoform X4

      UniProtKB/TrEMBL
      B2RWW2, E9QAH1
      Related
      ENSMUSP00000110460.2, ENSMUST00000114812.9
      Conserved Domains (4) summary
      COG1196
      Location:17962615
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK00252
      Location:49118
      alaS; alanyl-tRNA synthetase; Reviewed
      PRK12704
      Location:11261201
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:12902123
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    10. XM_011245881.2XP_011244183.1  golgin subfamily B member 1 isoform X2

      See identical proteins and their annotated locations for XP_011244183.1

      UniProtKB/TrEMBL
      B2RWW2
      Conserved Domains (4) summary
      COG1196
      Location:18312650
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK00252
      Location:49118
      alaS; alanyl-tRNA synthetase; Reviewed
      PRK12704
      Location:11611236
      PRK12704; phosphodiesterase; Provisional
      TIGR02168
      Location:13252158
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    11. XM_036159899.1XP_036015792.1  golgin subfamily B member 1 isoform X5

      UniProtKB/TrEMBL
      B2RWW2
      Conserved Domains (4) summary
      COG1196
      Location:17582577
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK00252
      Location:1180
      alaS; alanyl-tRNA synthetase; Reviewed
      TIGR02168
      Location:173958
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      NF033930
      Location:15061892
      pneumo_PspA; pneumococcal surface protein A

    RNA

    1. XR_003951781.2 RNA Sequence