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    Atp13a3 ATPase type 13A3 [ Mus musculus (house mouse) ]

    Gene ID: 224088, updated on 31-Jan-2019

    Summary

    Official Symbol
    Atp13a3provided by MGI
    Official Full Name
    ATPase type 13A3provided by MGI
    Primary source
    MGI:MGI:2685387
    See related
    Ensembl:ENSMUSG00000022533
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm541; Gm542; Gm1745; AU022875
    Expression
    Ubiquitous expression in bladder adult (RPKM 11.5), placenta adult (RPKM 10.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Atp13a3 in Genome Data Viewer
    Location:
    16; 16 B2
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (30312423..30388860, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (30312509..30388616, complement)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 15 Neighboring gene glycoprotein 5 (platelet) Neighboring gene transmembrane protein 44 Neighboring gene large 60S subunit nuclear export GTPase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cation transport IEA
    Inferred from Electronic Annotation
    more info
     
    cellular calcium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    probable cation-transporting ATPase 13A3
    Names
    type V P-type ATPase

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128094.1NP_001121566.1  probable cation-transporting ATPase 13A3 isoform 2

      See identical proteins and their annotated locations for NP_001121566.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. It encodes isoform 2 which is shorter than isoform 1.
      Source sequence(s)
      AC154608, BK005558
      Consensus CDS
      CCDS49820.1
      UniProtKB/Swiss-Prot
      Q5XF89
      Related
      ENSMUSP00000051645.6, ENSMUST00000061350.12
      Conserved Domains (6) summary
      TIGR01657
      Location:141142
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:232479
      E1-E2_ATPase; E1-E2 ATPase
      pfam00690
      Location:174222
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam12409
      Location:13141
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:618658
      Cation_ATPase; Cation transport ATPase (P-type)
      cl21460
      Location:817894
      HAD_like; Haloacid Dehalogenase-like Hydrolases
    2. NM_001128096.1NP_001121568.1  probable cation-transporting ATPase 13A3 isoform 1

      See identical proteins and their annotated locations for NP_001121568.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC154608
      Consensus CDS
      CCDS49821.1
      UniProtKB/Swiss-Prot
      Q5XF89
      Related
      ENSMUSP00000128224.1, ENSMUST00000100013.8
      Conserved Domains (6) summary
      TIGR01657
      Location:141142
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:232479
      E1-E2_ATPase; E1-E2 ATPase
      pfam00690
      Location:174222
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam12409
      Location:13141
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:618658
      Cation_ATPase; Cation transport ATPase (P-type)
      cl21460
      Location:854894
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      30312423..30388860 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011245879.2XP_011244181.1  probable cation-transporting ATPase 13A3 isoform X1

      Conserved Domains (6) summary
      TIGR01657
      Location:141115
      P-ATPase-V; P-type ATPase of unknown pump specificity (type V)
      pfam00122
      Location:205452
      E1-E2_ATPase; E1-E2 ATPase
      pfam00690
      Location:160195
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam12409
      Location:13141
      P5-ATPase; P5-type ATPase cation transporter
      pfam13246
      Location:591631
      Cation_ATPase; Cation transport ATPase (P-type)
      cl21460
      Location:827867
      HAD_like; Haloacid Dehalogenase-like Hydrolases
    2. XM_017316958.1XP_017172447.1  probable cation-transporting ATPase 13A3 isoform X2

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