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    Zc3h3 zinc finger CCCH type containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 223642, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zc3h3provided by MGI
    Official Full Name
    zinc finger CCCH type containing 3provided by MGI
    Primary source
    MGI:MGI:2663721
    See related
    Ensembl:ENSMUSG00000075600
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sm; Smicl; Zc3hdc3; BC049953; Kiaa0150
    Expression
    Ubiquitous expression in testis adult (RPKM 24.7), duodenum adult (RPKM 14.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Zc3h3 in Genome Data Viewer
    Location:
    15; 15 D3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (75626279..75713910, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (75754430..75842061, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (75584877..75672338, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene rhophilin, Rho GTPase binding protein 1 Neighboring gene v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) Neighboring gene predicted gene, 23747 Neighboring gene predicted gene, 34851 Neighboring gene predicted gene, 53897

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables R-SMAD binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables SMAD binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of mRNA cleavage and polyadenylation specificity factor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger CCCH domain-containing protein 3
    Names
    smad-interacting CPSF-like factor
    zinc finger CCCH type domain containing 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172121.1NP_742119.1  zinc finger CCCH domain-containing protein 3

      See identical proteins and their annotated locations for NP_742119.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ516034
      Consensus CDS
      CCDS27550.1
      UniProtKB/Swiss-Prot
      Q8CHP0
      UniProtKB/TrEMBL
      Q3UUL4
      Related
      ENSMUSP00000098106.3, ENSMUST00000100538.4
      Conserved Domains (2) summary
      smart00356
      Location:745771
      ZnF_C3H1; zinc finger
      pfam00642
      Location:663689
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      75626279..75713910 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017316551.1XP_017172040.1  zinc finger CCCH domain-containing protein 3 isoform X3

      Conserved Domains (2) summary
      COG5084
      Location:279386
      YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]
      pfam00642
      Location:384406
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    2. XM_011245566.3XP_011243868.1  zinc finger CCCH domain-containing protein 3 isoform X1

      Conserved Domains (2) summary
      COG5084
      Location:623730
      YTH1; Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins [General function prediction only]
      pfam00642
      Location:728750
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    3. XM_011245567.4XP_011243869.1  zinc finger CCCH domain-containing protein 3 isoform X2

    RNA

    1. XR_003951363.2 RNA Sequence

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