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    Ube2e1 ubiquitin-conjugating enzyme E2E 1 [ Mus musculus (house mouse) ]

    Gene ID: 22194, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ube2e1provided by MGI
    Official Full Name
    ubiquitin-conjugating enzyme E2E 1provided by MGI
    Primary source
    MGI:MGI:107411
    See related
    Ensembl:ENSMUSG00000021774
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    UbcM3; Ubce5; ubcM2
    Expression
    Ubiquitous expression in CNS E18 (RPKM 35.6), CNS E14 (RPKM 32.6) and 27 other tissues See more
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    Genomic context

    See Ube2e1 in Genome Data Viewer
    Location:
    14; 14 A1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (4137852..4186967)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (18282726..18332004, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (19115243..19164358, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32587 Neighboring gene predicted gene, 38620 Neighboring gene predicted gene, 22350 Neighboring gene predicted gene, 41098 Neighboring gene NFKB inhibitor interacting Ras-like protein 1 Neighboring gene ribosomal protein L15 Neighboring gene predicted gene 7084

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ISG15 transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ISG15 transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ubiquitin conjugating enzyme activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ubiquitin conjugating enzyme activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables ubiquitin conjugating enzyme activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in ISG15-protein conjugation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in ISG15-protein conjugation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H2B ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H2B ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone monoubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K48-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein K48-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein polyubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein ubiquitination IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ubiquitin-conjugating enzyme E2 E1
    Names
    (E3-independent) E2 ubiquitin-conjugating enzyme E1
    E2 ubiquitin-conjugating enzyme E1
    ubiquitin carrier protein E1
    ubiquitin-conjugating enzyme 5
    ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog
    ubiquitin-protein ligase E1
    NP_033481.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009455.3NP_033481.1  ubiquitin-conjugating enzyme E2 E1

      See identical proteins and their annotated locations for NP_033481.1

      Status: PROVISIONAL

      Source sequence(s)
      AK090177
      Consensus CDS
      CCDS26837.1
      UniProtKB/Swiss-Prot
      P52482
      UniProtKB/TrEMBL
      Q541Z5
      Related
      ENSMUSP00000022296.7, ENSMUST00000022296.7
      Conserved Domains (1) summary
      pfam00179
      Location:51188
      UQ_con; Ubiquitin-conjugating enzyme

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      4137852..4186967
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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