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    Ube2e1 ubiquitin-conjugating enzyme E2E 1 [ Mus musculus (house mouse) ]

    Gene ID: 22194, updated on 5-Aug-2018

    Summary

    Official Symbol
    Ube2e1provided by MGI
    Official Full Name
    ubiquitin-conjugating enzyme E2E 1provided by MGI
    Primary source
    MGI:MGI:107411
    See related
    Ensembl:ENSMUSG00000021774 Vega:OTTMUSG00000028840
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    UbcM3; Ubce5; ubcM2
    Expression
    Ubiquitous expression in CNS E18 (RPKM 35.6), CNS E14 (RPKM 32.6) and 27 other tissues See more

    Genomic context

    See Ube2e1 in Genome Data Viewer
    Location:
    14; 14 A2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (18282726..18331844, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (19115243..19164358, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene 7084 Neighboring gene NFKB inhibitor interacting Ras-like protein 1 Neighboring gene ribosomal protein L15 Neighboring gene predicted gene, 41098 Neighboring gene predicted gene, 32587 Neighboring gene predicted gene, 38620 Neighboring gene farnesyl diphosphate farnesyl transferase 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ISG15 transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ISG15 transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin conjugating enzyme activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ubiquitin conjugating enzyme activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    ubiquitin conjugating enzyme activity ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ISG15-protein conjugation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ISG15-protein conjugation ISO
    Inferred from Sequence Orthology
    more info
     
    histone H2B ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone H2B ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    histone monoubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    protein K48-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein K48-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    protein polyubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    protein ubiquitination IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ubiquitin-conjugating enzyme E2 E1
    Names
    (E3-independent) E2 ubiquitin-conjugating enzyme E1
    E2 ubiquitin-conjugating enzyme E1
    ubiquitin carrier protein E1
    ubiquitin-conjugating enzyme 5
    ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog
    ubiquitin-protein ligase E1
    NP_033481.1
    XP_011243061.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009455.3NP_033481.1  ubiquitin-conjugating enzyme E2 E1

      See identical proteins and their annotated locations for NP_033481.1

      Status: PROVISIONAL

      Source sequence(s)
      AK090177
      Consensus CDS
      CCDS26837.1
      UniProtKB/Swiss-Prot
      P52482
      UniProtKB/TrEMBL
      Q541Z5
      Related
      ENSMUSP00000022296.6, OTTMUSP00000036599, ENSMUST00000022296.6, OTTMUST00000071425
      Conserved Domains (1) summary
      pfam00179
      Location:51188
      UQ_con; Ubiquitin-conjugating enzyme

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      18282726..18331844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244759.1XP_011243061.1  ubiquitin-conjugating enzyme E2 E1 isoform X1

      Related
      ENSMUSP00000153693.1, ENSMUST00000225612.1
      Conserved Domains (2) summary
      COG5078
      Location:1152
      COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      pfam00179
      Location:12148
      UQ_con; Ubiquitin-conjugating enzyme
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