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    Rpl13a ribosomal protein L13A [ Mus musculus (house mouse) ]

    Gene ID: 22121, updated on 26-Sep-2022

    Summary

    Official Symbol
    Rpl13aprovided by MGI
    Official Full Name
    ribosomal protein L13Aprovided by MGI
    Primary source
    MGI:MGI:1351455
    See related
    Ensembl:ENSMUSG00000074129 AllianceGenome:MGI:1351455
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tstap198-7; tum-antigen; 1810026N22Rik
    Summary
    Enables mRNA binding activity. Involved in cellular response to interferon-gamma and negative regulation of translation. Acts upstream of or within several processes, including lung morphogenesis; macrophage chemotaxis; and response to lipopolysaccharide. Part of GAIT complex and ribonucleoprotein complex. Orthologous to human RPL13A (ribosomal protein L13a). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 459.7), bladder adult (RPKM 448.2) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rpl13a in Genome Data Viewer
    Location:
    7 B3; 7 29.14 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (44774987..44778169, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (45125563..45128745, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 45552 Neighboring gene microRNA 150 Neighboring gene small nucleolar RNA, C/D box 35B Neighboring gene ribosomal protein S11 Neighboring gene small nucleolar RNA, C/D box 35A Neighboring gene small nucleolar RNA, C/D box 34 Neighboring gene small nucleolar RNA, C/D box 32A Neighboring gene small nucleolar RNA, C/D box 33 Neighboring gene microRNA 5121 Neighboring gene FMS-like tyrosine kinase 3 ligand Neighboring gene aldehyde dehydrogenase 16 family, member A1 Neighboring gene PIH1 domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC107571

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cellular response to type II interferon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to type II interferon ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    PubMed 
    acts_upstream_of_or_within homeostatic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within lung morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within macrophage chemotaxis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of formation of translation preinitiation complex ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in negative regulation of translation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of translation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within response to lipopolysaccharide IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translation at postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in translation at presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IC
    Inferred by Curator
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    60S ribosomal protein L13a
    Names
    tissue specific transplantation antigen P198-7
    transplantation antigen P198
    tum-P198 antigen
    tum-transplantation antigen P198

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009438.5NP_033464.2  60S ribosomal protein L13a

      See identical proteins and their annotated locations for NP_033464.2

      Status: VALIDATED

      Source sequence(s)
      AV445288, BC042392, BC086896
      Consensus CDS
      CCDS21230.1
      UniProtKB/Swiss-Prot
      P19253
      UniProtKB/TrEMBL
      A0A8C6HLX2, Q5M9M0
      Related
      ENSMUSP00000115722.2, ENSMUST00000150350.9
      Conserved Domains (1) summary
      PTZ00068
      Location:6191
      PTZ00068; 60S ribosomal protein L13a; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      44774987..44778169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)